Implanon vs. Skyla

Are Implanon and Skyla the Same Thing?

Implanon (etonogestrel) and Skyla (levonorgestrel-releasing intrauterine system) are contraceptives used to prevent pregnancy for up to 3 years.

Implanon and Skyla are different forms of contraceptives. Implanon is a contraceptive implant and Skyla is an intrauterine device (IUD).

What Are Possible Side Effects of Implanon?

Common side effects of Implanon include:

Other side effects of Implanon include:

  • pain,
  • bruising,
  • numbness,
  • infection,
  • tingling,
  • minor bleeding, and
  • scarring at the site where the rod is placed

What Are Possible Side Effects of Skyla?

Common side effects of Skyla include:

What is Implanon?

Implanon (etonogestrel) is a contraceptive used to prevent pregnancy.

What is Skyla?

Skyla (levonorgestrel-releasing intrauterine system) is an intrauterine device (IUD) that contains the female hormone progestin, and is a contraceptive used to prevent pregnancy for up to 3 years.


Choosing Your Birth Control Method See Slideshow

What Drugs Interact With Implanon?

Implanon may interact with phenylbutazone, modafinil, St. John's wort, antibiotics, seizure medicines, barbiturates, and HIV medicines.

What Drugs Interact With Skyla?

Skyla may interact with barbiturates, St. John's wort, seizure medicines, and HIV medicines.

Skyla may also interact with grapefruit juice, bosentan, griseofulvin, rifabutin, rifampin, and non-nucleoside reverse transcriptase inhibitors.

How Should Implanon Be Taken?

The medicine in Implanon is contained in a small plastic rod that is implanted into the skin of your upper arm. The medicine dose is released slowly into the body. The rod can remain in place and provide continuous contraception for up to 3 years.

How Should Skyla Be Taken?

Skyla is available as one sterile intrauterine system with a 13.5 mg levonorgestrel dose. Skyla must be removed or replaced after 3 years. Other drugs may interact with Skyla. Tell your doctor all medications you use. Patients should avoid grapefruit juice while using Skyla. Women who have a current pelvic infection, get infections easily, or have certain cancers should not use Skyla. Pregnancy while using Skyla is uncommon but can be life threatening and may result in loss of pregnancy or fertility.


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RxList. Implanon Product Monograph.
RxList. Skyla Product Monograph.

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