- Are Imuran and Prednisone the Same Thing?
- What Are Possible Side Effects of Imuran?
- What Are Possible Side Effects of Prednisone?
- What is Imuran?
- What is Prednisone?
- What Drugs Interact with Imuran?
- What Drugs Interact with Prednisone?
- How Should Imuran Be Taken?
- How Should Prednisone Be Taken?
Are Imuran and Prednisone the Same Thing?
Imuran is also used to prevent the body from rejecting a transplanted kidney.
Prednisone is also used to treat or manage many conditions, including endocrine disorders, collagen diseases, dermatologic diseases, allergies, ophthalmic (eye) diseases, respiratory diseases, hematologic disorders, neoplastic diseases (cancers), edematous states, and gastrointestinal diseases.
Both Imuran and prednisone may interact with cyclosporine.
Prednisone may also interact with potassium-depleting agents (e.g., amphotericin B, diuretics), macrolide antibiotics, anticholinesterase, anticoagulants, antidiabetic drugs, isoniazid, bupropion, cholestyramine, digitalis glycosides, estrogens (including oral contraceptives), fluoroquinolones, barbiturates, phenytoin, carbamazepine, rifampin, azole antifungals, ritonavir, indinavir, nonsteroidal anti-inflammatory drugs (NSAIDs), quetiapine, skin tests, thalidomide, and live or inactivated vaccines.
What Are Possible Side Effects of Imuran?
Common side effects of Imuran include:
- upset stomach,
- loss of appetite,
- hair loss, or
- skin rash.
Tell your doctor if you experience unlikely but serious side effects of Imuran including:
- muscle loss,
- hair loss,
- cold/numbness in the fingers,
- mouth sores,
- difficult/painful swallowing, or
- greasy stools.
What Are Possible Side Effects of Prednisone?
Common side effects of Prednisone include:
- acne, thinning skin,
- weight gain,
- restlessness, and
- trouble sleeping.
Tell your doctor if you experience serious side effects of prednisone including
- severe allergic reactions (skin rash, itching, hives, swelling of your lips/face/tongue),
- mood changes or depression,
- eye pain or vision changes,
- sore throat,
- difficulty urinating, or
- high blood sugar (increased thirst, increased urination, confusion, or swelling of the ankles and feet).
What Is Imuran?
Imuran (azathioprine) is an immunosuppressive antimetabolite used to prevent the body from rejecting a transplanted kidney. Imuran is also used to treat symptoms of rheumatoid arthritis. Imuran is available in generic form.
What Is Prednisone?
Prednisone is a glucocorticoid indicated to treat or manage many conditions, including endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, allergies, ophthalmic (eye) diseases, respiratory diseases, hematologic disorders, neoplastic diseases (cancers), edematous states, and gastrointestinal diseases. Prednisone tablets are available in generic form.
What Drugs Interact With Imuran?
Imuran may interact with other medicines that weaken the immune system.
Imuran may interact with allopurinol, methotrexate, blood thinners, olsalazine, sulfasalazine, sulfamethoxasole, trimethoprim, or ACE inhibitors.
What Drugs Interact With Prednisone?
Prednisone may also interact with antibiotics, anticholinesterase, isoniazid, bupropion, cholestyramine, cyclosporine, digitalis glycosides, estrogens (including oral contraceptives), barbiturates, ritonavir, indinavir, nonsteroidal anti-inflammatory drugs (NSAIDs), quetiapine, skin tests, thalidomide, and live or inactivated vaccines.
Following prolonged therapy, withdrawal of corticosteroids such as dexamethasone or prednisone may result in symptoms of the corticosteroid withdrawal syndrome including muscle or joint pain and feeling unwell (malaise).
How Should Imuran Be Taken?
The dose of Imuran to prevent transplant rejection and minimize toxicity varies. The initial dose is usually 3 to 5 mg/kg daily, beginning at the time of transplant. It is usually given as a single daily dose on the day of, and in some cases 1 to 3 days before, transplantation. Maintenance levels of 1 to 3 mg/kg daily are usually possible. For rheumatoid arthritis, the initial dose is approx. 1.0 mg/kg (50 to 100 mg) given as a single dose or twice-daily. Maximum dose is 2.5 mg/kg per day.
How Should Prednisone Be Taken?
The initial dosage of prednisone may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated.
Rheumatoid Arthritis Resources
All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).
Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.
Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.
The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.
As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.
If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.
You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.
FDA. Prednisone Product Information.