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Inlyta

Last reviewed on RxList: 4/1/2019
Inlyta Patient Information Including Side Effects

Brand Names: Inlyta

Generic Name: axitinib

What is axitinib (Inlyta)?

Axitinib interferes with the growth of some cancer cells.

Axitinib is used to treat advanced kidney cancer.

Axitinib is usually given after other treatments have failed.

Axitinib may also be used for purposes not listed in this medication guide.

What are the possible side effects of axitinib (Inlyta)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some people taking axitinib have developed a perforation (a hole or tear) or a fistula (an abnormal passageway) within the stomach or intestines. Call your doctor if you have severe stomach pain, or if you feel like you are choking and gagging when you eat or drink.

Also call your doctor at once if you have:

  • chest pain or pressure, pain spreading to your jaw or shoulder, trouble breathing;
  • sudden numbness or weakness, problems with vision or speech;
  • headache, confusion, thinking problems, seizure (convulsions);
  • a light-headed feeling, like you might pass out;
  • easy bruising, unusual bleeding, purple or red spots under your skin;
  • heavy menstrual bleeding;
  • any bleeding that will not stop;
  • pink or brown urine;
  • heart problems--swelling, rapid weight gain, feeling short of breath;
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or
  • signs of a thyroid problem--sudden weight gain or loss, feeling very weak or tired, muscle pain, feeling hot or cold, hair loss, hoarse or deepened voice.

Common side effects may include:

  • nausea, vomiting, diarrhea, constipation;
  • rash, itching, redness, and peeling skin on your hands or feet;
  • feeling weak or tired;
  • increased blood pressure;
  • decreased appetite, weight loss; or
  • hoarse voice.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about axitinib (Inlyta)?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

Inlyta Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking axitinib (Inlyta)?

You should not use axitinib if you are allergic to it.

Tell your doctor if you have ever had:

You may need to have a negative pregnancy test before starting this treatment.

Both men and women using this medicine should use effective birth control to prevent pregnancy. Axitinib can cause harm an unborn baby if the mother or father is using this medicine.

Keep using birth control for at least 1 week after your last dose. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using axitinib.

This medicine may affect fertility (ability to have children) in both men and women. However, it is important to use birth control to prevent pregnancy because axitinib can harm an unborn baby.

It is not safe to breast-feed a baby while you are using this medicine. Also do not breast-feed for at least 2 weeks after your last dose.

How should I take axitinib (Inlyta)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Axitinib should be taken at evenly spaced intervals, usually once every 12 hours.

Take this medicine with a full glass of water. You may take axitinib with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

If you vomit shortly after taking axitinib, do not take another dose. Wait until your next scheduled dose time to take the medicine again.

Your blood pressure will need to be checked often. You may also need frequent medical tests.

If you need surgery, tell your surgeon you currently use axitinib. You will need to stop using the medicine at least 24 hours before a planned surgery.

Store at room temperature away from moisture and heat.

Inlyta Patient Information including If I Miss a Dose

What happens if I miss a dose (Inlyta)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose (Inlyta)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking axitinib (Inlyta)?

Grapefruit may interact with axitinib and lead to unwanted side effects. Avoid the use of grapefruit products.

This medicine can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient's body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.

What other drugs will affect axitinib (Inlyta)?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect axitinib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Inlyta)?

Your pharmacist can provide more information about axitinib.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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