Invega vs. Latuda

Are Invega and Latuda the Same Thing?

Invega (paliperidone) and Latuda (lurasidone hydrochloride) are antipsychotic medications used to treat schizophrenia.

Side effects of Invega and Latuda that are similar include drowsiness, dizziness, abdominal/stomach pain, nausea, weight gain, breast swelling or discharge, changes in menstrual periods, restlessness, shaking (tremors), blurred vision, decreased sex drive, impotence, or difficulty having an orgasm.

Side effects of Invega that are different from Latuda include headache, lightheadedness, upset stomach, cough, or dry mouth.

Side effects of Latuda that are different from Invega include diarrhea, loss of appetite, muscle stiffness, mask-like facial expression, inability to keep still, or agitation.

Both Invega and Latuda may interact with blood pressure medications, antibiotics, antidepressants, or other products that cause dizziness or drowsiness, including alcohol, antihistamines, drugs for sleep or anxiety, muscle relaxants, and narcotics.

Invega may also interact with arsenic trioxide, droperidol, anti-anxiety medications, anti-malaria medications, anti-seizure medications, heart rhythm medicine, medicine to prevent or treat nausea and vomiting, medicines to treat Parkinson's disease, medicines to treat psychiatric disorders, or migraine headache medicine.

Latuda may also interact with azole antifungals, HIV drugs, or rifamycins.

What Are Possible Side Effects of Invega?

Common side effects of Invega include:

  • drowsiness,
  • dizziness,
  • headache,
  • lightheadedness,
  • abdominal/stomach pain,
  • upset stomach,
  • nausea,
  • weight gain,
  • cough,
  • dry mouth,
  • breast swelling or discharge,
  • changes in menstrual periods,
  • restlessness,
  • shaking (tremor),
  • blurred vision,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

Tell your doctor if you have serious side effects of Invega including:

  • difficulty swallowing,
  • muscle spasms,
  • mental/mood changes, or
  • signs of infection (such as fever, persistent sore throat),
  • high fever,
  • sweating,
  • confusion,
  • fast or uneven heartbeats,
  • feeling like you might pass out,
  • tremors (uncontrolled shaking),
  • trouble swallowing,
  • sudden numbness or weakness, especially on one side of the body,
  • sudden and severe headache, or problems with vision, speech, or balance,
  • fever, chills, body aches, flu symptoms, or
  • white patches or sores inside your mouth or on your lips.

What Are Possible Side Effects of Latuda?

Common side effects of Latuda include:

  • drowsiness,
  • dizziness,
  • nausea,
  • diarrhea,
  • stomach pain,
  • loss of appetite,
  • shaking,
  • muscle stiffness,
  • weight gain,
  • mask-like facial expression,
  • inability to keep still,
  • restlessness,
  • agitation,
  • blurred vision,
  • breast swelling or discharge,
  • missed menstrual periods,
  • decreased sex drive,
  • impotence, or
  • difficulty having an orgasm.

Tell your doctor right if you experience serious side effects of Latuda including:

  • drooling,
  • trouble swallowing,
  • fainting,
  • signs of infection (such as persistent cough, fever)
  • fast or uneven or pounding heartbeats;
  • agitation, hostility, confusion, thoughts about hurting yourself,
  • seizures (convulsions),
  • fever, chills, body aches, flu symptoms,
  • sores in your mouth and throat,
  • high blood sugar (increased thirst, increased urination, hunger, dry mouth, fruity breath odor, drowsiness, dry skin, blurred vision, weight loss),
  • very stiff (rigid) muscles, high fever, sweating, confusion, tremors, feeling like you might pass out, or
  • twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.

What Is Invega?

Invega (paliperidone) extended-release tablets are indicated for the treatment of schizophrenia in adults and adolescents (12-17 years of age)

What Is Latuda?

Latuda (lurasidone hydrochloride) is an atypical antipsychotic used to treat schizophrenia.


Schizophrenia: Symptoms, Types, Causes, Treatment See Slideshow

What Drugs Interact With Invega?

If you are taking, or plan to take, any prescription or over-the-counter drugs, as there is a potential for interactions.

Do not drink alcohol while taking Invega.

What Drugs Interact With Latuda?

Latuda may interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), antibiotics, antifungal medications, or medications to treat HIV or AIDS.

Latuda may also interact with diltiazem or rifamycins.

How Should Invega Be Taken?

Invega should be taken with water. Tablets should not be chewed, divided, or crushed.

How Should Latuda Be Taken?

The recommended starting dose of Latuda is 40 mg once dxily, and it has been shown to be effective in a dose range of 40 mg/day to 160 mg/day.


Schizophrenia is the most disabling mental illness. See Answer

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Janssen Pharmaceuticals. Invega Product Information.

Sunovion Pharmaceuticals Inc. Latuda Drug Information.

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