Isopto Atropine

Last updated on RxList: 7/26/2018
Isopto Atropine Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 7/26/2018

Isopto Atropine (atropine sulfate ophthalmic solution) 1%, for topical ophthalmic use is a muscarinic antagonist indicated for dilation of the pupils (mydriasis), paralysis of the ciliary muscle of the eye, and penalization of the healthy eye in the treatment of lazy eye (amblyopia). Common side effects of Isopto Atropine include:

  • eye pain and stinging on administration,
  • blurred vision,
  • eye sensitivity to light,
  • eye inflammation,
  • decreased tearing,
  • drowsiness,
  • increased heart rate, and
  • increased blood pressure,
  • dry skin/mouth/throat,
  • drowsiness,
  • restlessness,
  • irritability, and
  • flushed skin of the face and neck.

In individuals from three (3) months of age or greater the dose of Isopto Atropine is 1 drop applied topically to the cul-de-sac of the conjunctiva, forty minutes prior to the intended maximal dilation time, In individuals 3 years of age or greater, doses of Isopto Atropine may be repeated up to twice daily as needed. Isopto Atropine may interact with monoamine oxidase inhibitors (MAOIs). Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Isopto Atropine; it is unknown if it will affect a fetus. It is unknown if Isopto Atropine passes into breast milk or if it would affect a nursing baby. Consult your doctor before breastfeeding.

Our Isopto Atropine (atropine sulfate ophthalmic solution) 1%, for topical ophthalmic use Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow
Isopto Atropine Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when atropine is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream.

Children can absorb larger amounts of the medicine and may be more likely to have side effects.

Call a doctor at once if the person using atropine ophthalmic has:

  • severe burning or stinging of the eyes;
  • severe eye redness or irritation;
  • fast heart rate, restlessness or irritability;
  • flushing (warmth, redness, or tingly feeling); or
  • increased blood pressure--severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety.

This medicine will cause blurred vision that could last up to 2 weeks. This may impair your reactions while driving or doing anything that requires you to be able to see clearly.

Common side effects may include:

  • mild stinging or pain when the drops are placed into your eye;
  • mild eye pain;
  • dry mouth, nose, or throat;
  • puffy or watery eyes;
  • blurred vision; or
  • your eyes may be more sensitive to light.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Isopto Atropine (Atropine Sulfate)

QUESTION

What causes dry eyes? See Answer
Isopto Atropine Professional Information

SIDE EFFECTS

The following adverse reactions are described below and elsewhere in the labeling:

The following adverse reactions have been identified following use of atropine sulfate ophthalmic solution. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Ocular Adverse Reactions

Eye pain and stinging occurs upon instillation of atropine sulfate ophthalmic solution. Other commonly occurring adverse reactions include blurred vision, photophobia, superficial keratitis and decreased lacrimation. Allergic reactions such as papillary conjunctivitis, contact dermatitis, and eyelid edema may also occur less commonly.

Systemic Adverse Reactions

Systemic effects of atropine are related to its anti-muscarinic activity. Systemic adverse events reported include dryness of skin, mouth, and throat from decreased secretions from mucus membranes; drowsiness; restlessness, irritability or delirium from stimulation of the central nervous system; tachycardia; flushed skin of the face and neck.

Read the entire FDA prescribing information for Isopto Atropine (Atropine Sulfate)

© Isopto Atropine Patient Information is supplied by Cerner Multum, Inc. and Isopto Atropine Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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