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Januvia vs. Jardiance

Medical and Pharmacy Editor:

Are Januvia and Jardiance the Same Thing?

Januvia (sitagliptin) and Jardiance (empagliflozin) are oral diabetes medicines for people with type 2 diabetes (non-insulin-dependent) diabetes.

Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes.

Jardiance is also indicated to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

Side effects of Januvia and Jardiance that are similar include joint pain or nausea.

Side effects of Januvia that are different from Jardiance include runny or stuffy nose, sore throat, headache, back pain, muscle pain, stomach pain, diarrhea, or constipation.

Side effects of Jardiance that are different from Januvia include dehydration, dizziness, lightheadedness, weakness, yeast infection, low blood sugar, upper respiratory tract infection, high cholesterol, increased urination, urinary tract infection (UTI), thirst, and low blood pressure (hypotension).

Both Januvia and Jardiance may interact with other anti-diabetic medications.

Januvia may also interact with digoxin, probenecid, nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers.

Jardiance may also interact with diuretics.

What Are Possible Side Effects of Januvia?

Common side effects of Januvia include:

  • runny or stuffy nose,
  • sore throat,
  • headache,
  • back pain,
  • joint or muscle pain,
  • nausea,
  • stomach pain,
  • diarrhea, or
  • constipation.

Although Januvia by itself usually does not cause low blood sugar (hypoglycemia), low blood sugar may occur if Januvia is prescribed with other anti-diabetic medications. Symptoms of low blood sugar include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet.

What Are Possible Side Effects of Jardiance?

Common side effects of Jardiance include:

What Is Januvia?

Januvia (sitagliptin) is an oral diabetes medicine for people with type 2 diabetes (non-insulin-dependent) diabetes. Januvia is sometimes used in combination with other diabetes medications, but is not for treating type 1 diabetes. Many people using Januvia do not have serious side effects.

What Is Jardiance?

Jardiance (empagliflozin) is an inhibitor of the sodium-glucose co-transporter 2 (SGLT2) used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Jardiance is also indicated to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

What Drugs Interact With Januvia?

Januvia may interact with digoxin, probenecid, non-steroidal anti-inflammatory drugs (NSAIDs), aspirin or other salicylates, sulfa drugs, monoamine oxidase inhibitors (MAOIs), or beta-blockers. Tell your doctor all prescription and over-the-counter medications you use. During pregnancy Januvia should be used only when prescribed. Pregnancy may cause or worsen diabetes. Your doctor may change your diabetes treatment during pregnancy. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Jardiance?

Jardiance may interact with diuretics, insulin or insulin secretagogues. Tell your doctor all medications and supplements you use. During pregnancy, Jardiance should be taken only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Januvia Be Taken?

The recommended dose of Januvia is 100 mg once daily.

How Should Jardiance Be Taken?

The recommended dose of Jardiance is 10 mg once daily in the morning, taken with or without food.

Reviewed on 3/13/2019

References:
Merck. Januvia Product Information.
https://www.januvia.com
Boehringer Ingelheim Pharmaceuticals, Inc. Jardiance Product Information.
www.jardiance.com/?

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