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Jardiance vs. Invokana

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Are Jardiance and Invokana the Same Thing?

Jardiance (empagliflozin) and Invokana (canagliflozin) are anti-diabetes medicines used as adjuncts to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Jardiance is also indicated to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

Side effects of Jardiance and Invokana that are similar include urinary tract infections (UTI), increased urination, weakness, infection, nausea, or thirst.

Side effects of Jardiance that are different from Invokana include dehydration, dizziness, lightheadedness, low blood sugar, upper respiratory tract infection, high cholesterol, joint pain, or low blood pressure (hypotension).

Side effects of Invokana that are different from Jardiance include vaginal itching, constipation, fatigue, skin sensitivity to sunlight, hypersensitivity reactions (including skin redness, rash, itching, hives, and swelling), bone fractures, or kidney problems.

Jardiance may interact with diuretics and insulin or insulin secretagogues.

Invokana may interact with rifampin or digoxin.

What Are Possible Side Effects of Jardiance?

Common side effects of Jardiance include:

What Are Possible Side Effects of Invokana?

Common side effects of Invokana include:

  • urinary tract infections,
  • increased urination,
  • yeast infections,
  • vaginal itching,
  • thirst,
  • constipation,
  • nausea,
  • fatigue,
  • weakness,
  • skin sensitivity to sunlight,
  • hypersensitivity reactions (including skin redness, rash, itching, hives, and swelling),
  • bone fractures, and
  • kidney problems.

What Is Jardiance?

Jardiance (empagliflozin) is an inhibitor of the sodium-glucose co-transporter 2 (SGLT2) used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Jardiance is also indicated to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

What Is Invokana?

Invokana (canagliflozin) is a sodium-glucose co-transporter 2 (SGLT2) inhibitor used to control blood sugar in people with type 2 diabetes mellitus, in addition to diet and exercise.

What Drugs Interact With Jardiance?

Jardiance may interact with diuretics, insulin or insulin secretagogues. Tell your doctor all medications and supplements you use. During pregnancy, Jardiance should be taken only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Invokana?

Invokana may interact with rifampin or digoxin. Tell your doctor all medications you use. Invokana should only be given to a pregnant woman if the benefit of the drug justifies the risk of harm to the fetus.

How Should Jardiance Be Taken?

The recommended dose of Jardiance is 10 mg once daily in the morning, taken with or without food.

How Should Invokana Be Taken?

The recommended starting dose of Invokana is 100 mg once daily, taken before the first meal of the day. Doses may be increased to 300 mg in patients who are able to tolerate Invokana at 100 mg doses.

Reviewed on 3/12/2019

References:
Boehringer Ingelheim Pharmaceuticals, Inc. Jardiance Product Information.
https://www.jardiance.com/
Janssen. Invokana Product Information.
https://www.invokana.com/

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