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Jardiance vs. Victoza

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Are Jardiance and Victoza the Same Thing?

Jardiance (empagliflozin) and Victoza (liraglutide [rDNA origin]) are anti-diabetes medicines used as adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Jardiance is also indicated to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

Side effects of Jardiance and Victoza that are similar include dizziness, nausea, or upper respiratory tract infection.

Side effects of Jardiance that are different from Victoza include dehydration, lightheadedness, weakness, yeast infection, low blood sugar, high cholesterol, joint pain, increased urination, urinary tract infection (UTI), thirst, and low blood pressure (hypotension).

Side effects of Victoza that are different from Jardiance include headache, vomiting, upset stomach, indigestion, loss of appetite, diarrhea, constipation, cold symptoms (stuffy nose, sneezing, sinus pain, sore throat), back pain, tired feeling, skin rash, or redness or rash where the medicine was injected.

Both Jardiance and Victoza may interact with insulin.

Jardiance may also interact with diuretics and insulin secretagogues.

Victoza may also interact with oral diabetes medicines.

What Are Possible Side Effects of Jardiance?

Common side effects of Jardiance include:

What Are Possible Side Effects of Victoza?

Common side effects of Victoza include:

  • headache,
  • dizziness,
  • nausea,
  • vomiting,
  • upset stomach,
  • indigestion,
  • loss of appetite,
  • diarrhea,
  • constipation,
  • cold symptoms (stuffy nose, sneezing, sinus pain, sore throat),
  • back pain,
  • tired feeling,
  • skin rash,
  • upper respiratory tract infection, or
  • redness or rash where the medicine was injected.

Tell your doctor if you have serious side effects of Victoza including:

  • swelling or a lump in your throat,
  • hoarse voice,
  • trouble swallowing,
  • shortness of breath,
  • urinating less than usual or not at all,
  • weakness,
  • confusion,
  • increased thirst,
  • loss of appetite,
  • pounding heartbeats or fluttering in your chest,
  • swelling,
  • weight gain,
  • pancreatitis (severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate),
  • signs of infection (such as fever, chills, sore throat, flu symptoms),
  • easy bruising or bleeding (nosebleeds, bleeding gums),
  • mouth sores, or
  • unusual weakness.

What Is Jardiance?

Jardiance (empagliflozin) is an inhibitor of the sodium-glucose co-transporter 2 (SGLT2) used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Jardiance is also indicated to reduce the risk of cardiovascular death in adult patients with type 2 diabetes mellitus and cardiovascular disease.

What Is Victoza?

Victoza (liraglutide [rDNA origin]) is a GLP-1 analog indicated for the treatment of type 2 diabetes mellitus as an adjunct to diet and exercise, to improve glycemic control in adults.

What Drugs Interact With Jardiance?

Jardiance may interact with diuretics, insulin or insulin secretagogues. Tell your doctor all medications and supplements you use. During pregnancy, Jardiance should be taken only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

What Drugs Interact With Victoza?

Patients should be advised that Victoza delays gastric emptying and may impact the absorption of concomitantly administered oral medications especially oral diabetes medications (Glucotrol, Metaglip, Amaryl, Avandaryl, Duetact, DiaBeta, Micronase, Glucovance, and others). Tell your doctor all medications and supplements you use. There are no adequate and well-controlled studies of Victoza in pregnant women. Victoza should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known if Victoza passes into breast milk. The patient and her healthcare provider should decide if Victoza will be taken or if the patient will breastfeed instead. Patients should not do both without consulting their healthcare providers first. Abrupt withdrawal of Victoza may lead to nausea and vomiting.

How Should Jardiance Be Taken?

The recommended dose of Jardiance is 10 mg once daily in the morning, taken with or without food.

How Should Victoza Be Taken?

Victoza should be injected subcutaneously in the abdomen, thigh, or upper arm once daily at any time of day. The injection site and timing can be changed without dose adjustment.

Reviewed on 3/12/2019

References:
Boehringer Ingelheim Pharmaceuticals, Inc. Jardiance Product Information.
https://www.jardiance.com/
Novo Nordisk. Victoza Product Information.
https://www.victoza.com/

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