Jenloga vs. Adderall

Are Jenloga and Adderall the Same Thing?

Jenloga (clonidine hydrochloride) extended release and Adderall (amphetamine and dextroamphetamine salts) are used to treat attention deficit hyperactivity disorder (ADHD).

Jenloga is also used to treat high blood pressure (hypertension).

Adderall is also used to treat narcolepsy.

Jenloga and Adderall belong to different drug classes. Jenloga is a central alpha agonist and Adderall is an amphetamine.

Side effects of Jenloga and Adderall that are similar include dry mouth, dizziness, constipation, headache, nausea, and trouble sleeping (insomnia).

Side effects of Jenloga that are different from Adderall include drowsiness and fatigue.

Side effects of Adderall that are different from Jenloga include nervousness, restlessness, excitability, irritability, agitation, fear, anxiety, agitation, tremor, weakness, blurred vision, unpleasant taste in the mouth, diarrhea, stomach pain, vomiting, fever, hair loss, loss of appetite, weight loss, loss of interest in sex, impotence, difficulty having an orgasm, increased blood pressure, increased heart rate, and heart palpitations.

Both Jenloga and Adderall may interact with antidepressants and barbiturates.

Jenloga may also interact with alcohol, narcotic pain relievers, and benzodiazepine sedatives such as alprazolam (Xanax) and clonazepam (Klonopin).

Adderall may also interact with heart or blood pressure medications, diuretics (water pills), cold or allergy medicines (antihistamines), seizure medications, acetazolamide, chlorpromazine, haloperidol, lithium, meperidine, methenamine, reserpine, ammonium chloride, fruit juices or ascorbic acid (vitamin C), potassium phosphate, antacids, sodium bicarbonate (Alka-Seltzer), potassium citrate, sodium citrate and citric acid, sodium citrate and potassium, and stomach acid reducers.

What Are Possible Side Effects of Jenloga?

Side effects of Jenloga include:

  • dry mouth
  • dizziness
  • drowsiness
  • fatigue
  • constipation
  • headache
  • nausea, or
  • trouble sleeping (insomnia)

What Are Possible Side Effects of Adderall?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using this medication and call your doctor at once if you have a serious side effect such as:

  • fast, pounding, or uneven heartbeats;
  • pain or burning when you urinate;
  • talking more than usual, feelings of extreme happiness or sadness;
  • tremors, hallucinations, unusual behavior, or motor tics (muscle twitches); or
  • dangerously high blood pressure (severe headache, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • headache, weakness, dizziness, blurred vision;
  • feeling restless, irritable, or agitated,
  • sleep problems (insomnia);
  • dry mouth or an unpleasant taste in your mouth;
  • diarrhea, constipation, stomach pain, nausea, vomiting;
  • fever;
  • hair loss, loss of appetite, weight loss; or
  • loss of interest in sex, impotence, or difficulty having an orgasm.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What Is Jenloga?

Jenloga (clonidine hydrochloride) extended release is a central alpha agonist used for high blood pressure (hypertension). Jenloga is also approved for the treatment of attention deficit hyperactivity disorder (ADHD).

What Is Adderall?

Adderall is a central nervous system stimulant prescription medicine. It is used for the treatment of Attention-Deficit Hyperactivity Disorder (ADHD). Adderall may help increase attention and decrease impulsiveness and hyperactivity in patients with ADHD.

Adderall should be used as a part of a total treatment program for ADHD that may include counseling or other therapies.

Adderall is also used in the treatment of a sleep disorder called narcolepsy.

Adderall is a federally controlled substance (CII) because it can be abused or lead to dependence. Keep Adderall in a safe place to prevent misuse and abuse. Selling or giving away Adderall may harm others, and is against the law.

What Drugs Interact With Jenloga?

Jenloga (clonidine hydrochloride) extended release is a central alpha agonist used for high blood pressure (hypertension). Jenloga is also approved for the treatment of attention deficit hyperactivity disorder (ADHD).

What Drugs Interact With Adderall?

Tell your doctor about all of the medicines that you or your child take including prescription and nonprescription medicines, vitamins, and herbal supplements.

Adderall and some medicines may interact with each other and cause serious side effects. Sometimes the doses of other medicines will need to be adjusted while taking Adderall.

Your doctor will decide whether Adderall can be taken with other medicines.

Especially tell your doctor if you or your child take:

  • anti-depression medicines including MAOIs
  • blood pressure medicines
  • seizure medicines
  • blood thinner medicines
  • cold or allergy medicines that contain decongestants
  • stomach acid medicines

Know the medicines that you or your child take. Keep a list of your medicines with you to show your doctor and pharmacist.

Do not start any new medicine while taking Adderall without talking to your doctor first.

How Should Jenloga Be Taken?

The recommended dose of Jenloga is 1 tablet, twice daily, or as directed by your doctor.

How Should Adderall Be Taken?

  • Take Adderall exactly as prescribed. Your doctor may adjust the dose until it is right for you or your child.
  • Adderall tablets are usually taken two to three times a day. The first dose is usually taken when you first wake in the morning. One or two more doses may be taken during the day, 4 to 6 hours apart.
  • Adderall can be taken with or without food.
  • From time to time, your doctor may stop Adderall treatment for a while to check ADHD symptoms.
  • Your doctor may do regular checks of the blood, heart, and blood pressure while taking Adderall. Children should have their height and weight checked often while taking Adderall. Adderall treatment may be stopped if a problem is found during these check-ups.
  • If you or your child take too much Adderall or overdoses, call your doctor or poison control center right away, or get emergency treatment.

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The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. assumes no responsibility for any healthcare administered to a person based on the information found on this site.

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If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the or websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.


FDA. Jenloga Product Information.

Shire. Adderall Product Information.

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