Joint pain can be caused by injury affecting any of the ligaments, bursae, or tendons surrounding the joint. Injury can also affect the ligaments, cartilage, and bones within the joint. Pain is also a feature of joint inflammation (arthritis, such as rheumatoid arthritis and osteoarthritis) and infection, and extremely rarely it can be a cause of cancer of the joint. Pain within the joint is a common cause of shoulder pain, ankle pain, and knee pain. Joint pain is also referred to as arthralgia. The sexually transmitted diseases (STDs) chlamydia and gonorrhea can lead to joint pain.
Symptoms and signs associated with joint pain can include
- joint redness,
- joint swelling,
- joint tenderness,
- joint warmth,
- locking of the joint,
- loss of range of motion of the joint,
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
Causes of Joint Pain
16 Early Symptoms and Signs of Rheumatoid Arthritis (RA)
Early RA symptoms and signs vary differently from person to person. The most common body parts that are initially affected by RA...
Ankle pain is commonly due to a sprain or tendinitis. The severity of ankle sprains ranges from mild (which can resolve within...
Arthritis is inflammation of one or more joints. When joints are inflamed they can develop stiffness, warmth, swelling, redness...
Aseptic necrosis (avascular necrosis or osteonecrosis) develops when blood supply diminishes to an area of bone and causes bone...
Broken Bone (Types of Bone Fractures)
A broken bone is a fracture. There are different types of fractures, such as: compressed, open, stress, greenstick,...
The bacteria Brucella causes brucellosis, an infectious zoonotic disease in humans. Symptoms and signs include fatigue, fever,...
The common bunion, an enlargement of the inner portion of the joint at the base of the big toe, primarily affects women. The...
A bursa is a fluid-filled sac found in the joints that cushions them. Bursitis is an inflammation of the bursae, most commonly...
Chikungunya Virus (Chikungunya Infection)
Chikungunya virus is an infection spread (transmitted) through a bite from an infected mosquito. Common symptoms of Chikungunya...
Chronic Fatigue Syndrome (CFS or SEID)
Chronic fatigue syndrome (CFS) or systemic exertion intolerance disease (SEID) is a debilitating and complex disorder...
Connective Tissue Disease
Connective tissue disease is when the body's connective tissues come under attack, possibly becoming injured by inflammation....
Dengue fever is contracted from the bite of a striped Aedes aegypti mosquito. Symptoms and signs of dengue include headache,...
The shoulder is the most often dislocated joint in the body due to its mobility. Dislocation occurs when the head of the humerus...
Ebola (Ebola Virus Disease or Ebola Hemorrhagic Fever)
Ebola hemorrhagic fever (HF) is an often-fatal disease that causes fever, headache, vomiting, diarrhea, sore throat, stomach...
Elbow pain is most often the result of tendinitis, which can affect the inner or outer elbow. Treatment includes ice, rest, and...
Fabry Disease (Symptoms and Life Expectancy)
Fabry disease (Fabry's disease, alpha-galactosidase-A) is a genetic disorder with symptoms such as burning sensations in...
Fibromyalgia is a chronic pain condition characterized by symptoms such as fatigue, sleep disturbances, and tender points. Stress...
Fungal arthritis is inflammation of a joint by a fungus that has invaded the body and is growing in the normally sterile joint....
German Measles (Rubella)
German measles is a disease that's caused by a virus. Symptoms include rash and fever for two to three days. The MMR (measles,...
Gout (Gouty Arthritis)
Buildup of uric acid crystals in a joint causes gouty arthritis. Symptoms and signs include joint pain, swelling, heat, and...
Graft Versus Host Disease (GVHD)
Graft versus host disease (GVHD) is a condition that happens when immune cells from transplanted donor tissue attack the...
Head and Neck Cancer
Head and neck cancer is cancer of the oral cavity, salivary glands, paranasal sinuses and nasal cavity, pharynx, larynx, or lymph...
Henoch-Schonlein purpura (HSP or anaphylactoid purpura), a type of blood vessel inflammation, results in rash, arthritis, and...
Hepatitis E Viral Infection
Hepatitis E (hep E) is a type of hepatitis viral infection that includes hepatitis A, B, C, D, F, which is caused by the...
Bursitis of the hip results when the fluid-filled sac (bursa) near the hip becomes inflamed due to localized soft tissue trauma...
Arthritis, bursitis, IT band syndrome, fracture, and strain are just some of the causes of hip pain. Associated symptoms and...
Human Immunodeficiency Virus (HIV)
The human immunodeficiency virus (HIV) causes HIV infection and the acquired immunodeficiency syndrome (AIDS). Symptoms and signs...
The joint hypermobility syndrome is a condition in which the joints easily move beyond the normal range expected for a particular...
Iliotibial Band Syndrome
Iliotibial band syndrome is an overuse injury of the thigh and knee. Symptoms include knee pain and possible swelling. Treatment...
Juvenile Idiopathic Arthritis (Juvenile Rheumatoid Arthritis)
Juvenile idiopathic arthritis (juvenile rheumatoid arthritis or JRA) annually affects one child in every thousand. There are six...
Bursitis of the knee results when any of the three fluid-filled sacs (bursae) become inflamed due to injury or strain. Symptoms...
Knee injuries, especially meniscus tears, are common in contact sports. Symptoms and signs of a torn meniscus include knee pain,...
Leukemia is a type of cancer of the blood cells in which the growth and development of the blood cells are abnormal. Strictly...
Lyme disease is a bacterial illness, which is spread by ticks when they bite the skin. Initially the disease affects the skin...
Osteoarthritis is a type of arthritis caused by inflammation, breakdown, and eventual loss of cartilage in the joints. Also...
With osteochondritis dissecans, bone and its adjacent cartilage loses its blood supply. Though osteochondritis dissecans can...
Pigmented Villonodular Synovitis (PVNS)
Pigmented villonodular synovitis (PVNS) is unusual growth of the tissue that lines the tendons in the body (synovium) and...
Plant Thorn Synovitis
Plant thorn synovitis (plant thorn arthritis) is joint inflammation caused by a thorn puncturing the joint and leaving residual...
Polymyalgia rheumatica (PMR) is a disorder of the muscles and joints that causes pain and stiffness in the arms, neck, shoulders,...
Pseudogout, a form of arthritis, results when deposits of crystals collect in and around the joints. Symptoms of pseudogout...
Psoriatic arthritis is a disease that causes skin and joint inflammation. Symptoms include painful, stiff, and swollen joints,...
Reactive arthritis is a chronic, systemic rheumatic disease characterized by three conditions, including conjunctivitis, joint...
Rheumatoid Arthritis (RA)
Rheumatoid arthritis (RA) is an autoimmune disease that causes chronic inflammation of the joints, the tissue around the joints,...
Rheumatoid Arthritis vs. Fibromyalgia
Though rheumatoid arthritis (RA) and fibromyalgia have similar symptoms, RA is an autoimmune disease and fibromyalgia is a...
Rheumatology is the study of rheumatic diseases and conditions. Rheumatologists are internal medicine physicians who treat these...
Sacroiliac Joint Dysfunction (SI Joint Pain)
Sacroiliac joint (SI) dysfunction is a general term to reflect pain in the SI joints. Causes of SI joint pain include...
Salmonella infection (salmonellosis) is typically caused by the consumption of contaminated foods. Symptoms of salmonellosis...
SAPHO syndrome is a chronic disorder that involves the skin, bone, and joints. SAPHO syndrome is an eponym for the combination of...
Septic arthritis, or infectious arthritis, is infection of one or more joints by bacteria, viruses, or fungi. Symptoms and signs...
Shoulder bursitis is inflammation of the shoulder bursa. Bursitis may be caused by injury, infection, or a rheumatic condition....
Sickle Cell Disease (Sickle Cell Anemia)
Sickle cell anemia (sickle cell disease), a blood disease which shortens life expectancy, is cause by an inherited abnormal...
Sjögren's syndrome is an autoimmune disease involving the abnormal production of extra antibodies that attack the glands and...
Sprains and Strains
An injury to a ligament is called a sprain, and an injury to muscle or tendon is called a strain. Sprains and strains may be...
STDs in Men
Sexually transmitted diseases (STDs) are infections transmitted during sexual contact. They may be caused by viruses, bacteria,...
Steroid Drug Withdrawal
Corticosteroid drugs such as prednisone and prednisolone are commonly used to treat asthma, allergic reactions, RA, and IBD....
Still's disease (systemic-onset juvenile rheumatoid arthritis) is a disorder characterized by inflammation with high fever...
Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis)
Sweet syndrome (acute febrile neutrophilic dermatosis) is a skin condition that sometimes occurs due to an immune system response...
Tennis Elbow (Lateral Epicondylitis)
Tennis elbow is also known as lateral epicondylitis. Symptoms of tennis elbow include tenderness and dull pain of the outer...
A toothache is a pain on or around a tooth. It may be caused by a variety of things from a cavity, abscess, or even sinusitis....
Torn ACL (Anterior Cruciate Ligament Tear)
The anterior cruciate ligament helps to prevent the top and bottom of the knee from sliding back and forth. Symptoms and signs of...
A torn meniscus (knee cartilage) may be caused by suddenly stopping, sharply twisting, or deep squatting or kneeling when lifting...
Typhus is a disease caused by Rickettsia bacteria. Symptoms and signs include fever, headache, nausea, vomiting, diarrhea, and...
Valley fever (coccidioidomycosis) is a disease caused by the inhalation of the Coccidioides immitis or C. posadasii fungus....
Zika Virus (Zika Fever)
The Zika virus is transmitted by the bite of an infected Aedes mosquito. Symptoms and signs of a Zika virus infection include...
Other Causes of Joint Pain
- Bone Tumor (Rare)
- Cartilage Tear
- Synovial Sarcoma (Rare)
Examples of Medications for Joint Pain
- acetaminophen (Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little Fevers Children's Fever/Pain)
- aspirin (acetylsalicylic acid, Bayer, Ecotrin, and others)
- ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, and others)
- Ketorolac vs. diclofenac
- Ketorolac vs. ibuprofen (Advil)
- Ketorolac vs. naproxen (Aleve)
- naproxen (Aleve, Anaprox, Naprelan, Naprosyn)
- Nonsteroidal Antiinflammatory Drugs (NSAIDs)
- OTC Pain Relievers and Fever Reducers