Karbinal ER

Last updated on RxList: 4/12/2021
Karbinal ER Side Effects Center

What Is Karbinal ER?

Karbinal ER (carbinoxamine maleate) is an H1 antagonist, a type of antihistamine, used to treat a wide variety of allergic reactions, including seasonal and perennial allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis, allergic skin manifestations of urticaria and angioedema, dermatographism, as therapy for anaphylactic reactions, and to improve the severity of allergic reactions to blood or plasma.

What Are Side Effects of Karbinal ER?

Common side effects of Karbinal ER include:

  • sleepiness,
  • drowsiness,
  • dizziness,
  • loss of coordination,
  • abdominal pain,
  • upset stomach,
  • constipation,
  • headache,
  • blurred vision,
  • dry mouth/nose/throat, and
  • thickening of mucus

Dosage for Karbinal ER

Karbinal ER is available as an extended-release oral suspension of 4 mg carbinoxamine maleate per 5 mL. Dosage depends of the age of the patient.

What Drugs, Substances, or Supplements Interact with Karbinal ER?

Karbinal ER may interact with monoamine oxidase inhibitors (MAOIs), alcohol, hypnotics, sedatives, tranquilizers or other substances that suppress the central nervous system. Tell your doctor all medications you use.

Karbinal ER During Pregnancy and Breastfeeding

It is unknown if Karbinal ER causes fetal harm when administered to a pregnant woman or if it can affect a woman's ability to reproduce, and should be given to a pregnant woman only if clearly needed. Karbinal ER should not be given to women who are currently breastfeeding.

Additional Information

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Our Karbinal ER (carbinoxamine maleate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Could I Be Allergic? Discover Your Allergy Triggers See Slideshow
Karbinal ER Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using carbinoxamine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • little or no urination;
  • wheezing, tightness in your chest;
  • pounding heartbeats or fluttering in your chest;
  • easy bruising or bleeding; or
  • pale or yellowed skin, dark colored urine, fever, confusion or weakness.

Side effects such as constipation, dizziness, and confusion may be more likely in older adults.

Common side effects may include:

  • drowsiness, dizziness;
  • loss of coordination;
  • dry mouth or nose;
  • upset stomach; or
  • feeling restless or excited (especially in children).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Karbinal ER (Carbinoxamine Maleate Extended-Release Oral Suspension)

QUESTION

Allergies can best be described as: See Answer
Karbinal ER Professional Information

SIDE EFFECTS

The following clinically significant adverse reactions are described else where in the labeling:

  • Somnolence and Impaired Mental Alertness [see WARNINGS AND PRECAUTIONS]
  • Allergic Reactions due to Sulfites, including Anaphylaxis [see WARNINGS AND PRECAUTIONS]

The most frequent adverse reactions include: sedation, sleepiness, dizziness, disturbed coordination, epigastic distress, and thickening of bronchial secretions. In clinical use, younger children and older adults may be particularly sensitive to adverse reactions [see Pediatric Use and Geriatric Use].

The following adverse reactions,listed by body system, have been identified in case reports and during the use of carbinoxamine in observational studies. Because these reactions are reported voluntarily from a population of uncertainsize, it is notalways possible to reliably estimate their frequencyor establish a causal relationship to drug exposure.

Body as a Whole: Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of mouth, nose and throat.

Cardiovascular: Hypotension, headache, palpitations, tachycardia, extrasystoles.

Central Nervous System: Fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomia, euphoria, paresthesia, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, hysteria, neuritis, convulsions.

Gastrointestinal: Anorexia,nausea, vomiting,diarrhea, constipation.

Hematologic: Hemolytic anemia, thrombocytopenia, agranulocytosis.

Laboratory: Increase in uric acid levels.

Respiratory: Tightness of chest and wheezing, nasal stuffiness.

Urogenital: Urinary frequency, difficult urination, urinaryretention, earlymenses.

DRUG INTERACTIONS

  • Do not use Karbinal ER in patients who are taking monoamine oxidase inhibitors (MAOIs), which prolong and intensify the anticholinergic (drying) effects of antihistamines.
  • Avoid use of Karbinal ER with alcohol and other CNS depressants (hypnotics sedatives, tranquilizers, etc.) due to additive effects.

Read the entire FDA prescribing information for Karbinal ER (Carbinoxamine Maleate Extended-Release Oral Suspension)

© Karbinal ER Patient Information is supplied by Cerner Multum, Inc. and Karbinal ER Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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