Lamisil vs. Jublia

Are Lamisil and Jublia the Same Thing?

Lamisil (terbinafine hydrochloride) and Jublia (efinaconazole) are antifungals used to treat infections caused by fungus that affect the fingernails or toenails (onychomycosis).

Lamisil and Jublia come in different forms. Lamisil is available as an oral medication. Lamisil oral granules are also used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old. Jublia is a topical solution.

What Are Possible Side Effects of Lamisil?

Common side effects of Lamisil include:

  • headache,
  • dizziness,
  • drowsiness,
  • stomach or abdominal pain,
  • upset stomach,
  • diarrhea,
  • heartburn,
  • loss of appetite, and
  • allergic reactions including skin inflammation, itching, rash, and unusual or unpleasant taste in your mouth.

What Are Possible Side Effects of Jublia?

Common side effects of Jublia include:

  • ingrown toenail,
  • inflammation,
  • pain, or
  • blisters at the application site

What is Lamisil?

Lamisil (terbinafine hydrochloride) is an antifungal antibiotic used to treat infections caused by fungus that affect the fingernails or toenails (onychomycosis). Oral granules are used to treat a fungal infection of scalp hair follicles in children who are at least 4 years old.

What is Jublia?

Jublia (efinaconazole) topical solution is an azole antifungal used for the topical treatment of fungal infection of the nail bed (onychomycosis) of the toenail(s) due to Trichophyton rubrum and Trichophyton mentagrophytes.

What Drugs Interact With Lamisil?

Lamisil may interact with cimetidine, rifampin, other antifungal antibiotics, blood thinners, heart rhythm medications, antidepressants, MAO inhibitors (MAOIs), or beta-blockers. Tell your doctor all medications you use. During pregnancy, Lamisil should be used only when prescribed.

What Drugs Interact With Jublia?

Jublia may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Jublia should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Lamisil Be Taken?

To treat fingernail onychomycosis the dose of Lamisil is one 250 mg tablet once daily for 6 weeks. For toenail onychomycosis, take one 250 mg tablet once daily for 12 weeks.

How Should Jublia Be Taken?

Apply a once-daily dose of Jublia to affected toenails for 48 weeks, using the integrated flow-through brush applicator.


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GSK. Lamisil Consumer Information.
Valeant Pharmaceuticals International, Inc. Jublia Product Information.

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