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Lasix vs. Aldactone

Are Lasix and Aldactone the Same Thing?

Lasix (furosemide) and Aldactone (spironolactone) are used to reduce edema (fluid accumulation) caused by heart, liver or kidney problems, or high blood pressure (hypertension).

Lasix may also be used with antihypertensive drugs to control high blood pressure (hypertension).

Aldactone is also used to reduce edema caused by certain patients with hyperaldosteronism.

Lasix and Aldactone belong to different drug classes. Lasix is an anthranilic acid derivative used as a strong loop diuretic and Aldactone is an aldosterone receptor antagonist.

What Are Possible Side Effects of Lasix?

Common side effects of Lasix include:

Serious side effects of Lasix include:

What Are Possible Side Effects of Aldactone?

Common side effects of Aldactone include:

  • skin rash,
  • headache,
  • dizziness,
  • nausea,
  • vomiting,
  • gas, and
  • stomach pain.

Tell your doctor if you have serious side effects of Aldactone including irregular heart rate, muscle pain or weakness, urinating less than usual, shallow breathing, tremors, confusion, or a severe skin reaction, hyperkalemia (high levels of potassium in the blood), and numbness.

What is Lasix?

Lasix (furosemide) is an anthranilic acid derivative that is used as a strong diuretic in adults and children to treat excessive fluid accumulation (edema) caused by congestive heart failure, liver failure, renal failure, and nephritic syndrome. Lasix may be used with antihypertensive drugs to control high blood pressure (hypertension).

What is Aldactone?

Aldactone (spironolactone) is an aldosterone receptor antagonist that causes the kidneys to remove water and sodium from the body, with reduced losses of potassium. Aldactone is used to reduce edema caused by heart, liver or kidney problems, high blood pressure (hypertension), and certain patients with hyperaldosteronism.

QUESTION

Salt and sodium are the same. See Answer

What Drugs Interact With Lasix?

Lasix may interact with lithium or steroids.

Lasix may also interact with sucralfate, cisplatin, cyclosporine, ethacrynic acid, methotrexate, phenytoin, antibiotics, heart or blood pressure medications, laxatives, or salicylates such as aspirin.

What Drugs Interact With Aldactone?

Aldactone may interact with lithium or steroids.

Aldactone may also interact with other medicines that make you sleepy (such as cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety), digoxin, ACE inhibitors, or nonsteroidal anti-inflammatory drugs (NSAIDs).

How Should Lasix Be Taken?

Lasix is available in tablet (20 to 80 mg) and IV forms. Dosage is determined by the patient's physician and varies according to how much fluid and how fast the fluid should be removed. Patients with poor renal function usually require higher doses; doses in children are weight-based. Lasix may interact with sucralfate, cisplatin, cyclosporine, ethacrynic acid, lithium, methotrexate, phenytoin, antibiotics, heart or blood pressure medications, laxatives, salicylates such as aspirin, or steroids. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant while using Lasix; it is unknown if it will harm a fetus. Lasix passes into breast milk and may harm a nursing baby. Lasix may also slow breast milk production. Consult your doctor before breastfeeding.

How Should Aldactone Be Taken?

Aldactone is available in 25, 50 and 100 mg tablets. Because of tumor formation in experimental animals, use in pregnancy should be avoided unless the benefits outweigh the potential risks to the fetus; women who are breastfeeding are advised not to use Aldactone. In addition, the drug should not be used to decrease the normal edema of pregnancy. An active metabolite of Aldactone appears in breast milk. Breastfeeding while using Aldactone is not recommended. If use of Aldactone is deemed essential, an alternative method of infant feeding should be used.

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References

RxList. Lasix Side Effects Drug Center.
https://www.rxlist.com/lasix-side-effects-drug-center.htm
RxList. Aldactone Side Effects Drug Center.
https://www.rxlist.com/aldactone-side-effects-drug-center.htm
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