Latisse Side Effects Center

Last updated on RxList: 9/8/2021
Latisse Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Latisse?

Latisse (bimatoprost) Ophthalmic Solution is a synthetic prostaglandin analog used to treat patients with not enough or inadequate eyelashes. Latisse is also used to treat glaucoma.

What Are Side Effects of Latisse?

Common side effects of Latisse include:

  • eye redness or discomfort,
  • eye itching,
  • dry eyes,
  • watery eyes, or eyelid redness, or puffy eyelids.

Other side effects of Latisse include hair growth on other areas of the skin where the medication frequently touches, and brown discoloration of the colored portion of the eye (iris) if used over months to years when the eye drop form is applied directly into the eyes to treat glaucoma.

Tell your doctor if you have serious side effects of Latisse including severe burning or itching of your eyes, severe redness or swelling in or around your eye, vision problems, eye pain, seeing halos around lights, oozing or discharge from your eye, or increased sensitivity to light.

Dosage for Latisse

Once nightly, place a one drop dose of Latisse 0.03% on the disposable sterile applicator supplied with the package and apply evenly along the skin of the upper eyelid margin at the base of the eyelashes. Blot excess solution runoff outside the upper eyelid margin with a tissue or absorbent cloth. Dispose of the applicator after one use. Repeat for the opposite eyelid margin using a new sterile applicator.

What Drugs, Substances, or Supplements Interact with Latisse?

Latisse may interact with glaucoma eye drops (such as bimatoprost, latanoprost, travoprost). Tell your doctor all medications and supplements you use.

Latisse During Pregnancy or Breastfeeding

During pregnancy, Latisse should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Latisse (bimatoprost) Ophthalmic Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Latisse Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • severe burning or itching of your eyes;
  • eye swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);
  • vision problems, eye pain, seeing halos around lights;
  • increased sensitivity to light; or
  • feeling like something is in your eye.

Common side effects may include:

  • eye redness or itching; or
  • darkening of the skin around your eyes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Latisse Professional Information


The following adverse reactions are described elsewhere in the labeling:

  • Effects on Intraocular Pressure [see WARNINGS AND PRECAUTIONS]
  • Iris Pigmentation [see WARNINGS AND PRECAUTIONS]
  • Lid Pigmentation [see WARNINGS AND PRECAUTIONS]
  • Hair Growth Outside the Treatment Area [see WARNINGS AND PRECAUTIONS]
  • Intraocular Inflammation [see WARNINGS AND PRECAUTIONS]
  • Macular Edema [see WARNINGS AND PRECAUTIONS]
  • Hypersensitivity [see CONTRAINDICATIONS]

Clinical Trial Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

The following information is based on clinical trial results from a multicenter, double-masked, randomized, vehicle-controlled, parallel study including 278 adult patients for four months of treatment.

The most frequently reported adverse reactions were eye pruritus, conjunctival hyperemia, skin hyperpigmentation, ocular irritation, dry eye symptoms, and periorbital erythema. These reactions occurred in less than 4% of patients. Additional adverse reactions seen in clinical trials experience include foreign body sensation, hair growth abnormal, and iris hyperpigmentation.

Additional adverse reactions reported with bimatoprost ophthalmic solution (LATISSE®) for the reduction of intraocular pressure include, ocular dryness, visual disturbance, ocular burning, eye pain, blepharitis, cataract, superficial punctate keratitis, eye discharge, tearing, photophobia, allergic conjunctivitis, asthenopia, conjunctival edema, iritis, infections (primarily colds and upper respiratory tract infections), headaches, and asthenia.

Postmarketing Experience

The following adverse reactions have been identified during postapproval use of LATISSE®. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The reactions include dry skin of the eyelid and/or periocular area, eye swelling, eyelid edema, hordeolum, hypersensitivity (local allergic reactions), lacrimation increased, madarosis and trichorrhexis (temporary loss of a few lashes to loss of sections of eyelashes, and temporary eyelash breakage, respectively), periorbital and lid changes associated with periorbital fat atrophy and skin tightness resulting in deepening of eyelid sulcus and eyelid ptosis, rash (including macular and erythematous), skin discoloration (periorbital), skin exfoliation of the eyelid and/or periorbital area, trichiasis, and vision blurred.


No Information Provided

Read the entire FDA prescribing information for Latisse (Bimatoprost Ophthalmic Solution 0.03% for Hypotrichosis)

© Latisse Patient Information is supplied by Cerner Multum, Inc. and Latisse Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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