Levo Dromoran

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 4/4/2022
Levo Dromoran Side Effects Center

What Is Levo Dromoran?

Levo Dromoran (levorphanol tartrate) is a narcotic pain reliever, similar to morphine, used to treat moderate to severe pain.

What Are Side Effects of Levo Dromoran?

Common side effects of Levo Dromoran include:

  • nausea,
  • vomiting,
  • stomach pain,
  • constipation,
  • dizziness,
  • lightheadedness,
  • drowsiness,
  • headache,
  • fatigue,
  • dry mouth,
  • sweating,
  • itching,
  • double vision or other vision problems, and
  • flushing (warmth, redness, or tingly feeling)

Dosage for Levo Dromoran

The recommended dosage of Levo Dromoran depends on whether it is in tablet or injectable form, as directed by your doctor.

What Drugs, Substances, or Supplements Interact with Levo Dromoran?

Levo Dromoran may interact with other medications for pain, MAO inhibitors, naltrexone, and cimetidine. Tell your doctor all medications you take. Do not drive, use machinery, or do any activity that requires alertness or clear vision while taking Levo Dromoran. Avoid alcoholic beverages.

Levo Dromoran During Pregnancy or Breastfeeding

Levo Dromoran should be used during pregnancy only if clearly needed. Levo Dromoran passes into breast milk. Consult your doctor if you are breastfeeding.

Additional Information

Our Levo Dromoran (levorphanol tartrate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Levo Dromoran Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should give naloxone and/or seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing, breathing that stops;
  • a slow heart rate or weak pulse;
  • a light-headed feeling, like you might pass out;
  • mood changes, unusual thoughts or behavior;
  • severe stomach pain, severe constipation;
  • high levels of serotonin in the body--agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, diarrhea; or
  • low cortisol levels-- nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Serious breathing problems may be more likely in older adults and those who are debilitated or have wasting syndrome or chronic breathing disorders.

Common side effects may include:

  • nausea, vomiting, stomach pain;
  • constipation;
  • dizziness, drowsiness;
  • tiredness; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Levo Dromoran (Levorphanol)

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Levo Dromoran Professional Information

SIDE EFFECTS

In approximately 1400 patients treated with Levo-Dromoran (levorphanol) in controlled clinical trials, the type and incidence of side effects were those expected of an opioid analgesic, and no unforeseen or unusual toxicity was reported.

Drugs of this type are expected to produce a cluster of typical opioid effects in addition to analgesia, consisting of nausea, vomiting, altered mood and mentation, pruritus, flushing, difficulties in urination, constipation and biliary spasm. The frequency and intensity of these effects appears to be dose related. Although listed as adverse events these are expected pharmacologic actions of these drugs and should be interpreted as such by the clinician.

The following adverse events have been reported with the use of Levo-Dromoran (levorphanol) :

Body as a Whole: abdominal pain, dry mouth, sweating

Cardiovascular System: cardiac arrest, shock, hypotension, arrhythmias including bradycardia and tachycardia, palpitations, extrasystoles

Digestive System: nausea, vomiting, dyspepsia, biliary tract spasm

Nervous System: coma, suicide attempt, convulsions, depression, dizziness, confusion, lethargy, abnormal dreams, abnormal thinking, nervousness, drug withdrawal, hypokinesia, dyskinesia, hyperkinesia, CNS stimulation, personality disorder, amnesia, insomnia

Respiratory System: apnea, cyanosis, hypoventilation

Skin & Appendages: pruritus, urticaria, rash, injection site reaction

Special Senses: abnormal vision, pupillary disorder, diplopia

Urogenital System: kidney failure, urinary retention, difficulty urinating

Drug Abuse And Dependence

Warning: May be Habit Forming

Levo-Dromoran (levorphanol) is a Schedule II Controlled Substance. All drugs of this class (mu-opioids of the morphine type) are habit forming and should be stored, prescribed, used and disposed of accordingly. Psychological/physical dependence and tolerance may develop upon repeated administration of Levo-Dromoran (levorphanol) .

Discontinuation of Levo-Dromoran (levorphanol) after chronic use has been reported to result in withdrawal syndromes, and some reports of overuse and self-reported addiction have been received. Neither withdrawal nor withdrawal symptoms are usually expected in postoperative patients who used the drug for less than a week or in patients who are gradually tapered off the drug after longer use.

Read the entire FDA prescribing information for Levo Dromoran (Levorphanol)

© Levo Dromoran Patient Information is supplied by Cerner Multum, Inc. and Levo Dromoran Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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