Levo-T Side Effects Center

Last updated on RxList: 4/4/2022
Levo-T Side Effects Center

What Is Levo-T?

Levo-T (levothyroxine sodium) a replacement for a hormone that is normally produced by your thyroid gland used to treat hypothyroidism (low thyroid hormone). Levo-T is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer. Levo-T is available in generic form.

What Are Side Effects of Levo-T?

Common side effects of Levo-T include hair loss during the first few months of treatment. This side effect of Levo-T is usually temporary as your body adjusts to this medication.

Other side effects of Levo-T include:

Dosage for Levo-T

Dosage of Levo-T is individualized. Levo-T may interact with lithium, amiodarone, antidepressants, or radiation therapy with iodine. Many other drugs can interact with Levo-T. Tell your doctor all medications and supplements you take. Other drugs can be taken while taking Levo-T, but they must be taken 4 hours before, or 4 hours after taking Levo-T. Consult your doctor.

What Drugs, Substances, or Supplements Interact with Levo-T?

Levo-T During Pregnancy or Breastfeeding

Current information shows Levo-T may be used during pregnancy. Tell your doctor if you are pregnant because your dose may need to be adjusted. This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.

Additional Information

Our Levo-T (levothyroxine sodium) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Where is the thyroid gland located? See Answer
Levo-T Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fast or irregular heartbeats;
  • chest pain, pain spreading to your jaw or shoulder;
  • shortness of breath;
  • fever, hot flashes, sweating;
  • tremors, or if you feel unusually cold;
  • weakness, tiredness, sleep problems (insomnia);
  • memory problems, feeling depressed or irritable;
  • headache, leg cramps, muscle aches;
  • feeling nervous or irritable;
  • dryness of your skin or hair, hair loss;
  • irregular menstrual periods; or
  • vomiting, diarrhea, appetite changes, weight changes.

Certain side effects may be more likely in older adults.

Common side effects may include:

  • chest pain, irregular heartbeats;
  • shortness of breath;
  • headache, leg cramps, muscle pain or weakness;
  • tremors, feeling nervous or irritable, trouble sleeping;
  • increased appetite;
  • feeling hot;
  • weight loss;
  • changes in your menstrual periods;
  • diarrhea; or
  • skin rash, partial hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Hyperthyroidism Symptoms and Treatment See Slideshow
Levo-T Professional Information

SIDE EFFECTS

Adverse reactions associated with LEVO-T therapy are primarily those of hyperthyroidism due to therapeutic overdosage [see WARNINGS AND PRECAUTIONS, OVERDOSE]. They include the following:

  • General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating
  • Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia
  • Musculoskeletal: tremors, muscle weakness, muscle spasm
  • Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest
  • Respiratory: dyspnea
  • Gastrointestinal: diarrhea, vomiting, abdominal cramps, elevations in liver function tests
  • Dermatologic: hair loss, flushing, rash
  • Endocrine: decreased bone mineral density
  • Reproductive: menstrual irregularities, impaired fertility

Seizures have been reported rarely with the institution of levothyroxine therapy.

Adverse Reactions In Children

Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height.

Hypersensitivity Reactions

Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various gastrointestinal symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness, and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.

Read the entire FDA prescribing information for Levo-T (Levothyroxine Sodium Tablets)

© Levo-T Patient Information is supplied by Cerner Multum, Inc. and Levo-T Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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