Medical Editor: John P. Cunha, DO, FACOEP
Levo-T (levothyroxine sodium) a replacement for a hormone that is normally produced by your thyroid gland used to treat hypothyroidism (low thyroid hormone). Levo-T is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer. Levo-T is available in generic form. Common side effects of Levo-T include hair loss during the first few months of treatment. This side effect of Levo-T is usually temporary as your body adjusts to this medication. Other side effects of Levo-T include:
- allergic reactions (hives, itching, skin rash, and flushing),
- abdominal pain,
- joint pain, and
Dosage of Levo-T is individualized. Levo-T may interact with lithium, amiodarone, antidepressants, or radiation therapy with iodine. Many other drugs can interact with Levo-T. Tell your doctor all medications and supplements you take. Other drugs can be taken while taking Levo-T, but they must be taken 4 hours before, or 4 hours after taking Levo-T. Consult your doctor. Current information shows Levo-T may be used during pregnancy. Tell your doctor if you are pregnant because your dose may need to be adjusted. This medication passes into breast milk but is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.
Our Levo-T (levothyroxine sodium) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
- General: fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating
- Central nervous system: headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia
- Musculoskeletal: tremors, muscle weakness, muscle spasm
- Cardiovascular: palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest
- Respiratory: dyspnea
- Gastrointestinal: diarrhea, vomiting, abdominal cramps, elevations in liver function tests
- Dermatologic: hair loss, flushing, rash
- Endocrine: decreased bone mineral density
- Reproductive: menstrual irregularities, impaired fertility
Seizures have been reported rarely with the institution of levothyroxine therapy.
Adverse Reactions In Children
Pseudotumor cerebri and slipped capital femoral epiphysis have been reported in children receiving levothyroxine therapy. Overtreatment may result in craniosynostosis in infants and premature closure of the epiphyses in children with resultant compromised adult height.
Hypersensitivity reactions to inactive ingredients have occurred in patients treated with thyroid hormone products. These include urticaria, pruritus, skin rash, flushing, angioedema, various gastrointestinal symptoms (abdominal pain, nausea, vomiting and diarrhea), fever, arthralgia, serum sickness, and wheezing. Hypersensitivity to levothyroxine itself is not known to occur.
Read the entire FDA prescribing information for Levo-T (Levothyroxine Sodium Tablets)