Levothyroxine Sodium Side Effects Center

Last updated on RxList: 7/18/2016
Levothyroxine Sodium Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 7/18/2016

Levothyroxine sodium (levothyroxine sodium anhydrous injection) is an L-thyroxine product indicated for the treatment of myxedema coma. Levothyroxine sodium is available in generic form. Common side effects of levothyroxine sodium include signs and symptoms compatible with hyperthyroidism, such as:

An initial intravenous loading dose of levothyroxine sodium for injection between 300 to 500 mcg followed by once daily intravenous maintenance doses between 50 and 100 mcg should be administered, as clinically indicated, until the patient can tolerate oral therapy. Levothyroxine sodium may interact with antidiabetics or insulin, oral anticoagulants, digitalis glycosides, tricyclic or tetracyclic antidepressants, ketamine, sympathomimetics, or thyroid hormone. Tell your doctor all medications and supplements you use. During pregnancy, levothyroxine sodium should be taken as prescribed. Pregnant patients who develop myxedema should be treated with levothyroxine sodium as the risk of non-treatment is associated with a high probability of significant morbidity or mortality to the mother and the fetus. Consult your doctor before breastfeeding. Adequate replacement doses of thyroid hormones are required to maintain normal lactation. /p>

Our Levothyroxine sodium (levothyroxine sodium anhydrous injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Where is the thyroid gland located? See Answer
Levothyroxine Sodium Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fast or irregular heartbeats;
  • chest pain, pain spreading to your jaw or shoulder;
  • shortness of breath;
  • fever, hot flashes, sweating;
  • tremors, or if you feel unusually cold;
  • weakness, tiredness, sleep problems (insomnia);
  • memory problems, feeling depressed or irritable;
  • headache, leg cramps, muscle aches;
  • feeling nervous or irritable;
  • dryness of your skin or hair, hair loss;
  • irregular menstrual periods; or
  • vomiting, diarrhea, appetite changes, weight changes.

Certain side effects may be more likely in older adults.

Common side effects may include:

  • chest pain, irregular heartbeats;
  • shortness of breath;
  • headache, leg cramps, muscle pain or weakness;
  • tremors, feeling nervous or irritable, trouble sleeping;
  • increased appetite;
  • feeling hot;
  • weight loss;
  • changes in your menstrual periods;
  • diarrhea; or
  • skin rash, partial hair loss.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Levothyroxine Sodium (Levothyroxine Sodium Anhydrous Injection, Powder, Lyophilized, for Solution)

SLIDESHOW

Hyperthyroidism Symptoms and Treatment See Slideshow
Levothyroxine Sodium Professional Information

SIDE EFFECTS

Excessive doses of levothyroxine can predispose to signs and symptoms compatible with hyperthyroidism. The signs and symptoms of thyrotoxicosis include, but are not limited to: exophthalmic goiter, weight loss, increased appetite, palpitations, nervousness, diarrhea, abdominal cramps, sweating, tachycardia, increased pulse and blood pressure, cardiac arrhythmias, angina pectoris, tremors, insomnia, heat intolerance, fever, and menstrual irregularities.

Read the entire FDA prescribing information for Levothyroxine Sodium (Levothyroxine Sodium Anhydrous Injection, Powder, Lyophilized, for Solution)

© Levothyroxine Sodium Patient Information is supplied by Cerner Multum, Inc. and Levothyroxine Sodium Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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