Medical Editor: John P. Cunha, DO, FACOEP
What Is Levsin SL?
Levsin SL (hyoscyamine sulfate) is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids used to treat many different stomach and intestinal disorders, including peptic ulcer and irritable bowel syndrome. Levsin SL is also used to control muscle spasms in the bladder, kidneys, or digestive tract, and to reduce stomach acid, and is sometimes used to reduce tremors and rigid muscles in people with symptoms of Parkinson's disease. Levsin SL may be available in generic form.
What Are Side Effects of Levsin SL?
Common side effects of Levsin SL include:
- dizziness,
- drowsiness,
- blurred vision,
- dry mouth,
- vision problems,
- headache,
- trouble sleeping (insomnia),
- constipation,
- flushing,
- dry skin,
- decreased sweating,
- nervousness,
- nausea,
- vomiting,
- bloating,
- heartburn,
- changes in taste,
- problems with urination,
- impotence,
- loss of interest in sex, or
- trouble having an orgasm.
Tell your doctor if you have unlikely but serious side effects of Levsin SL including:
- mental/mood changes (e.g., confusion, unusual excitement),
- fast or irregular heartbeat,
- loss of coordination, or
- slurred speech.
Dosage for Levsin SL
The dose of Levsin SL for adults and children 12 years of age and older is 1 to 2 tablets every four hours or as needed. Do not exceed 12 tablets in 24 hours. For pediatric patients 2 to under 12 years of age: ½ to 1 tablet every four hours or as needed. Do not exceed 6 tablets in 24 hours. Tablets may be taken sublingually, orally or chewed.
What Drugs, Substances, or Supplements Interact with Levsin SL?
Levsin SL may interact with amantadine, haloperidol, MAO inhibitors, phenothiazines, or antidepressants. Tell your doctor all medications and supplements you use.
Levsin SL During Pregnancy or Breastfeeding
Levsin SL should be used only when prescribed during pregnancy. This drug passes into breast milk. Consult your doctor before breastfeeding.
Additional Information
Our Levsin SL (hyoscyamine sulfate) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW
Digestive Disorders: Common Misconceptions See SlideshowGet emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using hyoscyamine and call your doctor at once if you have:
- anxiety, confusion, hallucinations, unusual thoughts or behavior;
- weakness, memory problems;
- slurred speech;
- problems with balance or muscle movement;
- diarrhea; o
- pounding heartbeats or fluttering in your chest.
Common side effects may include:
- dizziness, drowsiness, feeling weak or tired;
- decreased sweating, decreased urination;
- blurred vision;
- rash;
- dry mouth, decreased sense of taste;
- stomach pain, nausea, vomiting, bloating;
- diarrhea, constipation;
- headache;
- sleep problems (insomnia); or
- impotence, loss of interest in sex, or trouble having an orgasm.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION
What is irritable bowel syndrome or IBS? See AnswerSIDE EFFECTS
All of the following adverse reactions have been reported with hyoscyamine sulfate. Adverse reactions may include dryness of the mouth; urinary hesitancy and retention; blurred vision; tachycardia; palpitations; mydriasis; increased ocular tension; loss of taste; headache; nervousness; drowsiness; weakness; fatigue; dizziness; insomnia; nausea; vomiting; impotence; constipation; bloated feeling; abdominal pain; diarrhea; allergic reactions or drug idiosyncrasies; urticaria and other dermal manifestations; ataxia; speech disturbance; some degree of mental confusion and/or excitement (especially in elderly persons); short-term memory loss; hallucinations; and decreased sweating.
Read the entire FDA prescribing information for Levsin SL (Hyoscyamine Sulfate Tablets)
© Levsin SL Patient Information is supplied by Cerner Multum, Inc. and Levsin SL Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.
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