Lexette

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 8/25/2021
Lexette Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Lexette?

Lexette (halobetasol propionate) is a corticosteroid used for the topical treatment of plaque psoriasis in patients 18 years of age and older.

What Are Side Effects of Lexette?

Side effects of Lexette include:

Dosage for Lexette

Apply Lexette as a thin uniform film to the affected skin twice daily for up to two weeks. Rub in gently. Wash hands after applying the product.

Lexette In Children

Safety and effectiveness of Lexette in patients younger than 18 years of age have not been established.

What Drugs, Substances, or Supplements Interact with Lexette?

Lexette may interact with other medicines.

Tell your doctor all medications and supplements you use.

Lexette During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Lexette; it is unknown how it would affect a fetus. There are no data on the presence of Lexette or its metabolites in human milk, the effects on the breastfed infant, or the effects on milk production after topical application to women who are breastfeeding. Breastfeeding women are advised not to apply Lexette directly to the nipple and/or areola to avoid direct infant exposure. Consult your doctor before breastfeeding.

Additional Information

Our Lexette (halobetasol propionate) Topical Foam Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Psoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off. See Answer
Lexette Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

  • burning, stinging, itching, or dryness of treated skin;
  • pain where the foam was applied;
  • redness or crusting around your hair follicles;
  • stretch marks;
  • spider veins;
  • headache; or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Lexette (Halobetasol Propionate Topical Foam)

SLIDESHOW

Types of Psoriasis: Medical Pictures and Treatments See Slideshow
Lexette Professional Information

SIDE EFFECTS

The following adverse reactions are discussed in greater detail in other sections of the label:

  • Hypothalamic-Pituitary-Adrenal (HPA) Axis Suppression and Other Adverse Endocrine Effects [see WARNINGS AND PRECAUTIONS]
  • Allergic Contact Dermatitis [see WARNINGS AND PRECAUTIONS]

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

In randomized, multicenter, vehicle-controlled clinical trials, 351 adults with plaque psoriasis were treated with LEXETTE twice daily for up to two weeks (up to approximately 50 grams per week). Table 1 presents selected adverse reactions that occurred in at least 1% of subjects.

Table 1: Adverse Reactions Occurring in ≥ 1% of Subjects through Week 2

HBP Foam
N=351
Vehicle Foam
N=353
Adverse Reaction%%
  Application site burning/stinging12%15%
  Application site pain1%<1%
  Headache1%<1%

Skin atrophy (n=1) and telangiectasia (n=2) were reported with LEXETTE, but not with vehicle foam.

Read the entire FDA prescribing information for Lexette (Halobetasol Propionate Topical Foam)

© Lexette Patient Information is supplied by Cerner Multum, Inc. and Lexette Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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