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Lialda vs. Pentasa

Medical and Pharmacy Editor:

Are Pentasa and Lialda the Same Thing?

Lialda (mesalamine) and Pentasa (mesalamine) are aminosalicylate anti-inflammatory agents used to treat ulcerative colitis, proctitis, and proctosigmoiditis, and also to prevent the symptoms of ulcerative colitis from recurring.

What Are Possible Side Effects of Lialda?

Common side effects of Lialda include:

  • nausea,
  • vomiting,
  • stomach cramps,
  • diarrhea,
  • gas,
  • fever,
  • sore throat,
  • flu-like symptoms,
  • constipation,
  • headache,
  • dizziness,
  • tired feeling, or
  • skin rash.

Contact your doctor if you experience serious side effects of Lialda including:

  • severe stomach pain,
  • fever,
  • headache, and
  • bloody diarrhea.

What Are Possible Side Effects of Pentasa?

Common side effects of Pentasa include:

  • diarrhea,
  • headache,
  • nausea,
  • vomiting,
  • stomach cramps,
  • gas,
  • fever,
  • sore throat,
  • other flu symptoms,
  • constipation,
  • dizziness,
  • tired feeling, or
  • skin rash.

Infrequently, Pentasa can worsen ulcerative colitis. Tell your doctor if your symptoms worsen after starting Pentasa (such as increased abdominal pain or cramping, bloody diarrhea, and fever). Tell your doctor if you have serious side effects of Pentasa including:

  • changes in the amount of urine,
  • dark urine,
  • persistent nausea or vomiting,
  • severe stomach or abdominal pain,
  • yellowing eyes or skin,
  • chest pain, or
  • shortness of breath.

What is Lialda?

Lialda (mesalamine) is an anti-inflammatory agent used to treat ulcerative colitis, proctitis, and proctosigmoiditis, and also to prevent the symptoms of ulcerative colitis from recurring.

What is Pentasa?

Pentasa (mesalamine) is an anti-inflammatory agent used to treat ulcerative colitis, proctitis, and proctosigmoiditis. Pentasa is also used to prevent the symptoms of ulcerative colitis from recurring.

What Drugs Interact With Lialda?

Lialda may interact with azathioprine or mercaptopurine, pentamidine, tacrolimus, amphotericin B, antibiotics, antiviral medicines, cancer medicine, aspirin or other NSAIDs. Tell your doctor all medications you are taking. Lialda is not expected to be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. This medication can pass into breast milk and may harm a nursing baby. Do not use this medication if you are breastfeeding.

What Drugs Interact With Pentasa?

Pentasa may interact with pazathioprine or mercaptopurine, pentamidine, tacrolimus, amphotericin B, antibiotics, antiviral medicines, cancer medicine, or aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs).

How Should Lialda Be Taken?

The recommended dosage of Lialda for the induction of remission in adult patients with active, mild to moderate ulcerative colitis is two to four 1.2 g tablets taken once daily with a meal for a total daily dose of 2.4 g or 4.8 g. The recommended dosage for the maintenance of remission is two 1.2 g tablets taken once daily with a meal for a total daily dose of 2.4 g.

How Should Pentasa Be Taken?

The recommended dosage of Pentasa for the induction of remission and the symptomatic treatment of mildly to moderately active ulcerative colitis is 1g (four 250 mg capsules or two 500 mg capsules) 4 times a day for a total daily dosage of 4g. Treatment duration may be up to 8 weeks.

Reviewed on 10/11/2018

References:
Shire Pharmaceutical. Lialda Product Information.
http://www.lialda.com/
Shire Pharmaceutical. Pentasa Product Information.
https://www.pentasaus.com/

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