Linzess

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 07/12/2021
Linzess Patient Information Including Side Effects

Brand Names: Linzess

Generic Name: linaclotide

What is linaclotide (Linzess)?

Linaclotide is used to treat chronic constipation, or chronic irritable bowel syndrome (IBS) in people who have had constipation as the main symptom.

Linaclotide may also be used for purposes not listed in this medication guide.

What are the possible side effects of linaclotide (Linzess)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using linaclotide and call your doctor at once if you have:

  • severe or ongoing diarrhea; or
  • diarrhea with dizziness or a light-headed feeling (like you might pass out).

Common side effects may include:

  • diarrhea;
  • stomach pain;
  • gas; or
  • bloating or full feeling in your stomach.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about linaclotide (Linzess)?

You should not use linaclotide if you have a blockage in your intestines.

Linaclotide is not approved for use by anyone younger than 18 years old.

Linaclotide should not be given to a child younger than 6 years old. Linaclotide can cause severe diarrhea and fatal dehydration in a child.

QUESTION

What is irritable bowel syndrome or IBS? See Answer
Linzess Patient Information including How Should I Take

3 pharmacies near 20147 have coupons for Linzess (Brand Names:Linzess for 30 Capsules)

CVS Pharmacy
CVS Pharmacy
$21.39

Est. Regular Price

$424.49

with free coupon

View Coupon
Walgreens
Walgreens
$577.99

Est. Regular Price

$431.99

with free coupon

View Coupon
Costco
Costco
$577.99

Est. Regular Price

$437.88

with free coupon

View Coupon

What should I discuss with my healthcare provider before taking linaclotide (Linzess)?

You should not use linaclotide if you are allergic to it, or if you have:

  • a blockage in your intestines (bowel obstruction).

Linaclotide is not approved for use by anyone younger than 18 years old.

Linaclotide should not be given to a child younger than 6 years old. Linaclotide can cause severe diarrhea and fatal dehydration in a child. Do not give this medicine to any child or teenager without the advice of a doctor.

Tell your doctor if you are pregnant or breastfeeding.

How should I take linaclotide (Linzess)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Take linaclotide in the morning on an empty stomach, at least 30 minutes before your first meal.

Swallow the capsule whole and do not crush, chew, break, or open it.

If you cannot swallow a capsule whole, open it and sprinkle the medicine into a spoonful of applesauce or bottled water. Swallow the mixture right away without chewing. Do not save it for later use.

Even if you have taken this medicine with applesauce, wait at least 30 minutes before eating a full meal.

If needed, medicine from the linaclotide capsule may be given through a nasogastric (NG) or gastronomy tube.

Carefully follow instructions for mixing medicine from the capsule with applesauce or water, or giving the medicine through a feeding tube. Ask your doctor or pharmacist if you have any questions.

It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.

Keep this medicine out of the reach of children. Linaclotide can be fatal to a child who accidentally swallows this medicine. Seek emergency medical attention if this happens.

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow
Linzess Patient Information including If I Miss a Dose

What happens if I miss a dose (Linzess)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose (Linzess)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking linaclotide (Linzess)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect linaclotide (Linzess)?

Other drugs may affect linaclotide, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Linzess)?

Your pharmacist can provide more information about linaclotide.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Health Solutions From Our Sponsors