American Liverleaf, Anemone acutiloba, Anémone à Lobes Aigus, Anemone americana, Anemone hepatica, Anémone d'Amérique, Anémone Hépatique, Bryopsidée, Hepatica nobilis var. acuta, Hepatica nobilis var. obtusa, Hepática, Hepatici Noblis Herba, Hépatique d'Amérique, Hépatique à Lobes Aigus, Herb Trinity, Kidney Wort, Leberbluemchenkraut, Liverleaf, Liverweed, Liverwort-Leaf, Round-Leaved Hepatica, Round-Lobe Hepatica, Sharp-Lobe Hepatica, Trefoil.
Liverwort is a plant. People make medicine out of the fresh or dried parts that grow above the ground.
Despite serious safety concerns, liverwort is used for treating gallstones and liver conditions including jaundice, liver enlargement, hepatitis, and liver cirrhosis. It is also used for treating stomach and digestive tract discomfort, stimulating appetite, relieving sensation of fullness, regulating bowel function, and stimulating the pancreas.
Some people use liverwort for treating varicose veins, lowering cholesterol, stimulating blood circulation, and “purifying” blood.
Women use liverwort for relieving symptoms of menopause.
Other uses include strengthening nerves, stimulating metabolism, promoting relaxation, and as a general tonic.
Liverwort is sometimes applied directly to hemorrhoids.
How does it work?
Liverwort might stimulate the central nervous system (CNS).
Insufficient Evidence to Rate Effectiveness for...
- Liver conditions such as hepatitis or cirrhosis.
- Stomach and digestive discomfort.
- Poor appetite.
- High cholesterol.
- Varicose veins.
- Poor blood circulation.
- Menopausal symptoms.
- Regulating bowel function.
- Stimulating the pancreas.
- Strengthening nerves.
- Stimulating metabolism.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
Fresh liverwort is LIKELY UNSAFE when taken by mouth or applied to the skin. It can cause many side effects such as diarrhea, stomach irritation, and kidney and urinary tract irritation when taken by mouth. When applied directly to the skin, fresh liverwort can cause irritation, itching, and pus-filled blisters.
It isn’t known if dried liverwort is safe or what the side effects might be.
The appropriate dose of liverwort depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for liverwort. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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Storrs, F. J., Mitchell, J. C., and Rasmussen, J. E. Contact hypersensitivity to liverwort and the compositae family of plants. Cutis 1976;18(5):681-686. View abstract.
Tamehiro, N., Sato, Y., Suzuki, T., Hashimoto, T., Asakawa, Y., Yokoyama, S., Kawanishi, T., Ohno, Y., Inoue, K., Nagao, T., and Nishimaki-Mogami, T. Riccardin C: a natural product that functions as a liver X receptor (LXR)alpha agonist and an LXRbeta antagonist. FEBS Lett 10-10-2005;579(24):5299-5304. View abstract.