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Locoid Lipocream

Last reviewed on RxList: 2/17/2017
Locoid Lipocream Side Effects Center

Last reviewed on RxList 02/17/2017

Locoid Lipocream (hydrocortisone butyrate) Cream, 0.1% is a topical (for the skin) steroid used to treat inflammation of the skin caused by a number of conditions such as allergic reactions, eczema, or psoriasis. Locoid Lipocream is available in generic form. Common side effects of Locoid Lipocream include stinging, burning, itching, irritation, dryness, redness, or peeling at the application site when this medication is first applied to the skin. These side effects should disappear in a few days as your body adjusts to Locoid Lipocream. Other side effects of Locoid Lipocream include:

Tell your doctor if you have serious side effects Locoid Lipocream including:

  • blurred vision,
  • seeing halos around lights,
  • uneven heartbeats,
  • sleep problems (insomnia),
  • weight gain,
  • puffiness in your face, or
  • feeling tired.

Apply a thin film dose of Locoid Lipocream to the affected skin areas two or three times daily, depending on the severity of the condition. Rub in gently. Locoid Lipocream may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Locoid Lipocream should be used only if prescribed. It is unknown if this drug passes into breast milk when applied to the skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breastfeeding.

Our Locoid Lipocream (hydrocortisone butyrate) Cream, 0.1% Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Locoid Lipocream Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Locoid Lipocream (Hydrocortisone Butyrate)

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Locoid Lipocream Professional Information

SIDE EFFECTS

The following adverse reactions are discussed in greater detail in other sections of the labeling:

Clinical Trials Experience: Adults

The following additional local adverse reactions have been reported infrequently with topical corticosteroids but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence: burning, itching, irritation, drying, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae and miliaria.

Clinical Trials Experience: Pediatrics

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice. The safety data derived from Locoid Lipocream (hydrocortisone butyrate) clinical trials reflect exposure to Locoid Lipocream twice daily for up to four weeks in separate clinical trials involving pediatric subjects 3 months to 18 years of age with mild to moderate atopic dermatitis.

Adverse reactions shown in the tables below include those for which there is some basis to believe there is a causal relationship to Locoid Lipocream (hydrocortisone butyrate) .

Table 1 : Frequency of adverse reactions in pediatric subjects with mild to moderate atopic dermatitis

  Locoid Lipocream
(N=131)
Vehicle
(N=133 )
Application site reactions, including application site folliculitis, irritation, dermatitis, or erythema 1.5% 1.5%
Acne 0.8% 0.0%
Telangiectasia 0.0% 0.8%

Postmarketing Experience

The following adverse reactions have been identified during post approval use of Locoid Lipocream (hydrocortisone butyrate) . Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

Skin: Erythema, Rash and Application site irritation.

Read the entire FDA prescribing information for Locoid Lipocream (Hydrocortisone Butyrate)

Related Resources for Locoid Lipocream

Read the Locoid Lipocream User Reviews »

© Locoid Lipocream Patient Information is supplied by Cerner Multum, Inc. and Locoid Lipocream Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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