LoKara Side Effects Center

Last updated on RxList: 4/4/2022
LoKara Side Effects Center

What Is LoKara?

LoKara (desonide 0.05%) lotion is a low to medium potency corticosteroid indicated for the relief of the inflammatory and pruritic (itching) manifestations of corticosteroid responsive dermatoses. LoKaralotion is available in generic form.

What Are Side Effects of LoKara?

Common side of LoKara lotion include:

Dosage for LoKara

Each gram of LoKara Lotion (desonide lotion 0.05%) contains 0.5 mg of desonide in a lotion base in two sizes, 59 and 118ml. LoKara should be applied to the affected areas as a thin film two or three times daily depending on the severity of the condition. Therapy should be discontinued when control is achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary.

What Drugs, Substances, or Supplements Interact with LoKara?

LoKara lotion may interact with other drugs. Tell your doctor all medications and supplements you use. It is also not known whether LoKara can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.

LoKara During Pregnancy or Breastfeeding

LoKara should be given to a pregnant woman only if clearly needed. Because many drugs are excreted in human milk, caution should be exercised when LoKara is administered to a nursing woman. Safety and effectiveness has not been done for pediatric patients.

Additional Information

Our LoKara Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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LoKara Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Steroid medicine can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

  • stinging or burning of treated skin;
  • skin irritation, redness, itching, or hardening;
  • dry, scaly, or oily skin;
  • swelling in your hands or feet;
  • acne, stretch marks; or
  • redness or crusting around your hair follicles.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for LoKara (Desonide Lotion 0.05%)


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LoKara Professional Information


In controlled clinical trials, the total incidence of adverse reactions associated with the use of desonide was approximately 8%. These were: stinging and burning approximately 3%, irritation, contact dermatitis, condition worsened, peeling of skin, itching, intense transient erythema, and dryness/scaliness, each less than 2%.

The following additional local adverse reactions have been reported infrequently with other topical corticosteroids, and they may occur more frequently with the use of occlusive dressings, especially with higher potency corticosteroids. These reactions are listed in an approximate decreasing order of occurrence: folliculitis, acneiform eruptions, hypopigmentation, perioral dermatitis, secondary infection, skin atrophy, striae, and miliaria.

Read the entire FDA prescribing information for LoKara (Desonide Lotion 0.05%)

© LoKara Patient Information is supplied by Cerner Multum, Inc. and LoKara Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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