Lopid vs. Lipitor

Are Lopid and Lipitor the Same Thing?

Lopid (gemfibrozil) and Lipitor (atorvastatin) are used to lower cholesterol levels.

Lopid is also used to treat very high cholesterol and triglyceride levels in people with pancreatitis.

Lipitor is also used to elevate HDL ("good") cholesterol.

Lopid and Lipitor belong to different drug classes, Lopid is a lipid-regulating agent and Lipitor is an HMG-CoA reductase inhibitor (a "statin" drug).

Side effects of Lopid and Lipitor that are similar include nausea, diarrhea, headache, and muscle pain.

Side effects of Lopid that are different from Lipitor include stomach upset, stomach/abdominal pain, vomiting, dizziness, drowsiness, joint pain, loss of interest in sex, impotence, difficulty having an orgasm, numbness or tingly feeling, unusual taste, or cold symptoms (such as stuffy nose, sneezing, sore throat).

Side effects of Lipitor that are different from Lopid include constipation, fatigue, gas, and heartburn.

Both Lopid and Lipitor may interact with other cholesterol-lowering drugs and alcohol.

Lopid may also interact with blood thinners, insulin or oral diabetes medications, and colchicine.

Lipitor may also interact with antibiotics, antifungals, birth control pills, heart medications, or medicines to treat HIV/AIDS.

What Are Possible Side Effects of Lopid?

Common side effects of Lopid include:

  • stomach upset,
  • stomach/abdominal pain,
  • nausea,
  • vomiting,
  • diarrhea,
  • headache,
  • dizziness,
  • drowsiness,
  • joint or muscle pain,
  • loss of interest in sex,
  • impotence,
  • difficulty having an orgasm,
  • numbness or tingly feeling,
  • unusual taste, or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

Lopid may infrequently cause gallstones and liver problems.

Tell your doctor if you notice any of the following unlikely, but serious side effects of Lopid including:

  • severe stomach/abdominal pain,
  • persistent nausea or vomiting,
  • yellowing eyes or skin, and
  • dark urine.

What Are Possible Side Effects of Lipitor?

Common side effects of Lipitor include:

  • trouble sleeping (insomnia),
  • dry mouth,
  • cough,
  • decreased appetite,
  • upset stomach,
  • nausea or vomiting,
  • dizziness,
  • drowsiness,
  • problems urinating,
  • irritability,
  • constipation,
  • skin rash,
  • itching,
  • increased menstrual cramps, and
  • sexual side effects including
    • impotence,
    • loss of interest in sex, or
    • trouble having an orgasm.

What Is Lopid?

Lopid (gemfibrozil) is a lipid regulating agent used to treat very high cholesterol and triglyceride levels in people with pancreatitis, and is also used to lower the risk of stroke, heart attack, or other heart complications in people with high cholesterol and triglycerides who have not been helped by other treatments. Lopid is available in generic form.

What Is Lipitor?

Lipitor (atorvastatin) is a statin used for the treatment of elevated total cholesterol, LDL, triglycerides, and to elevate HDL cholesterol.


How to Lower Your Cholesterol & Save Your Heart See Slideshow

What Drugs Interact With Lopid?

Lopid may interact with blood thinners, insulin or oral diabetes medication, or other cholesterol-lowering drugs. Tell your doctor all medications you use. Lopid is not recommended for use during pregnancy. It is unknown if this medication passes into breast milk.

What Drugs Interact With Lipitor?

Erythromycin (E-Mycin), ketoconazole (Nizoral), itraconazole (Sporanox), cyclosporine (Sandimmune), indinavir (Crixivan) and ritonavir (Norvir) decrease elimination of Lipitor. Lipitor increases the effect of warfarin (Coumadin) and cholestyramine (Questran) decreases the absorption of Lipitor.

How Should Lopid Be Taken?

The recommended dose of Lopid for adults is 1200 mg administered in two divided doses 30 minutes before the morning and evening meals.

How Should Lipitor Be Taken?

The recommended dose of Lipitor is 10-80 mg daily.


What is cholesterol? See Answer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.


Pfizer. Lopid Prescribing Information.
Lipitor Prescribing Information.

Health Solutions From Our Sponsors