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Lopid vs. Lovaza

Reviewed on 5/14/2019

Are Lopid and Lovaza the Same Thing?

Lopid (gemfibrozil) and Lovaza (omega-3-acid ethyl esters) are used to treat high triglyceride levels.

Lopid is also used to treat very high cholesterol and triglyceride levels in people with pancreatitis, and is also used to lower the risk of stroke, heart attack, or other heart complications in people with high cholesterol and triglycerides who have not been helped by other treatments.

Lopid and Lovaza belong to different drug classes. Lopid is a lipid regulating agent and Lovaza is a combination of fatty acids.

Side effects of Lopid and Lovaza that are similar include stomach upset and unusual or unpleasant taste in your mouth.

Side effects of Lopid that are different from Lovaza include stomach/abdominal pain, nausea, vomiting, diarrhea, headache, dizziness, drowsiness, joint or muscle pain, loss of interest in sex, impotence, difficulty having an orgasm, numbness or tingly feeling, unusual taste, or cold symptoms (such as stuffy nose, sneezing, sore throat).

Side effects of Lovaza that are different from Lopid include back pain, belching, and skin rash.

Both Lopid and Lovaza may interact with blood thinners and alcohol.

Lopid may also interact with insulin or oral diabetes medications, other cholesterol-lowering drugs, or colchicine.

Lovaza may also interact with birth control pills or hormone replacement, beta-blockers, or diuretics (water pills).

What Are Possible Side Effects of Lopid?

Common side effects of Lopid include:

  • stomach upset,
  • stomach/abdominal pain,
  • nausea,
  • vomiting,
  • diarrhea,
  • headache,
  • dizziness,
  • drowsiness,
  • joint or muscle pain,
  • loss of interest in sex,
  • impotence,
  • difficulty having an orgasm,
  • numbness or tingly feeling,
  • unusual taste, or
  • cold symptoms such as stuffy nose, sneezing, sore throat.

Lopid may infrequently cause gallstones and liver problems.

Tell your doctor if you notice any of the following unlikely, but serious side effects of Lopid including:

  • severe stomach/abdominal pain,
  • persistent nausea or vomiting,
  • yellowing eyes or skin, and
  • dark urine.

What Are Possible Side Effects of Lovaza?

Common side effects of Lovaza include:

  • back pain,
  • upset stomach,
  • burping,
  • skin rash, and
  • unusual or unpleasant taste in your mouth.

Tell your doctor if you experience rare but very serious side effects of Lovaza including:

  • easy bleeding/bruising,
  • black or tarry stool, or
  • vomit that looks like coffee grounds.

What Is Lopid?

Lopid (gemfibrozil) is a lipid regulating agent used to treat very high cholesterol and triglyceride levels in people with pancreatitis, and is also used to lower the risk of stroke, heart attack, or other heart complications in people with high cholesterol and triglycerides who have not been helped by other treatments. Lopid is available in generic form.

What Is Lovaza?

Lovaza (omega-3-acid ethyl esters) is a combination of fatty acids used together with diet and exercise to help lower triglyceride levels in the blood. Lovaza is made of omega-3 polyunsaturated fatty acids, which are found in oil from fish, vegetables, and other plant sources. These fatty acids are not made by the body and must be consumed in the diet.

QUESTION

What are triglycerides? See Answer

What Drugs Interact With Lopid?

Lopid may interact with blood thinners, insulin or oral diabetes medication, or other cholesterol-lowering drugs. Tell your doctor all medications you use. Lopid is not recommended for use during pregnancy. It is unknown if this medication passes into breast milk.

What Drugs Interact With Lovaza?

Lovaza may interact with birth control pills or hormone replacement, blood thinners, beta-blockers, or diuretics (water pills). Tell your doctor all medications you use. Lovaza should be used only when prescribed during pregnancy. It is not known if this medication passes into breast milk. Consult your doctor before breastfeeding.

How Should Lopid Be Taken?

The recommended dose of Lopid for adults is 1200 mg administered in two divided doses 30 minutes before the morning and evening meals.

How Should Lovaza Be Taken?

The daily dose of Lovaza is 4 grams per day, taken as a single 4-gram dose (4 capsules) or as two 2-gram doses (2 capsules given twice daily).

SLIDESHOW

How to Lower Your Cholesterol & Save Your Heart See Slideshow
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References

Pfizer. Lopid Prescribing Information.
https://www.pfizermedicalinformation.com/en-us/lopid/dosage-admin
GlaxoSmithKline. Lovaza Prescribing Information.
https://www.gsksource.com/pharma/content/dam/GlaxoSmithKline/US/en/Prescribing_Information/Lovaza/pdf/LOVAZA-PI-PIL.PDF

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