Lotemax Ophthalmic Ointment

Last updated on RxList: 1/13/2021
Lotemax Ophthalmic Ointment Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Lotemax Ophthalmic?

Lotemax Ophthalmic Ointment (loteprednol etabonate) is a corticosteroid indicated for the treatment of post-operative inflammation and pain following ocular (eye) surgery. Lotemax Ophthalmic Ointment is available as a generic named loteprednol etabonate eye drops.

What Are Side Effects of Lotemax Ophthalmic?

Side effects of Lotemax Ophthalmic Ointment include:

  • minor burning when using the eye drops
  • feeling that something is in your eye
  • being more sensitive to light
  • headache
  • runny nose
  • sore throat
  • dry/red/itchy/watery eyes and elevated intraocular (inside the eye) pressure which may be associated with optic nerve damage
  • cataract formation, and
  • herpes simplex

Dosage for Lotemax Ophthalmic

Lotemax (loteprednol etabonate) is supplied as a 3.5 gram tube filled with loteprednol etabonate ophthalmic ointment (0.5% strength of Lotemax). Lotemax is dosed in approximately ½ inch ribbons into the conjunctival sac(s) four times daily beginning 24 hours after surgery and continuing throughout the first two weeks of the post-operative period.

What Drugs, Substances, or Supplements Interact with Lotemax Ophthalmic?

Ophthalmic Ointment may interact with other drugs. Tell your doctor all medications and supplements you use.

Lotemax Ophthalmic During Pregnancy and Breastfeeding

Lotemax should be used during pregnancy only if the potential benefit justifies the potential risk to the embryo or fetus. It is not known whether topical ophthalmic administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Caution should be exercised when Lotemax ointment is administered to a nursing woman. Serious side effects are eye infections, glaucoma and thinning of eye tissue. The safety and efficacy of this drug is not available for pediatric patients.

Additional Information

Our Lotemax Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Lotemax Ophthalmic Ointment Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pain when using the eye drops;
  • worsening redness or itching;
  • eye pain or swelling, trouble closing your eye;
  • pain behind your eyes, sudden vision changes;
  • tunnel vision, seeing halos around lights; or
  • signs of eye infection--redness, severe discomfort, crusting or drainage.

Common side effects may include:

  • minor burning when using the eye drops;
  • eye pain, blurred vision;
  • dry or watery eyes;
  • feeling like something is in your eye;
  • your eyes may be more sensitive to light;
  • headache; or
  • runny nose, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Lotemax Ophthalmic Ointment (loteprednol etabonate)


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Lotemax Ophthalmic Ointment Professional Information


Adverse reactions associated with ophthalmic steroids include elevated intraocular pressure, which may be associated with optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, secondary ocular infection from pathogens including herpes simplex, and perforation of the globe where there is thinning of the cornea or sclera.

The most common ocular adverse event reported at approximately 25% in subjects in clinical studies with LOTEMAX ointment was anterior chamber inflammation. Other common adverse events, with an incidence of 4-5%, were conjunctival hyperemia, corneal edema, and eye pain. Many of these events may have been the consequence of the surgical procedure. The only non-ocular adverse event occurring at ≥ 1% was headache (1.5%).

Read the entire FDA prescribing information for Lotemax Ophthalmic Ointment (loteprednol etabonate)

© Lotemax Ophthalmic Ointment Patient Information is supplied by Cerner Multum, Inc. and Lotemax Ophthalmic Ointment Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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