Last updated on RxList: 4/23/2021
Lotensin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Lotensin?

Lotensin (benazepril hydrochloride) is an angiotensin-converting enzyme (ACE) inhibitor used to treat patients with high blood pressure (hypertension). Lotensin is available in generic form.

What Are Side Effects of Lotensin?

Common side effects of Lotensin are:

  • dizziness,
  • cough,
  • headache,
  • nausea,
  • vomiting,
  • constipation,
  • drowsiness,
  • dizziness,
  • lightheadedness,
  • tired feeling,
  • anxiety,
  • sleep problems (insomnia),
  • flushing (warmth, redness, or tingly feeling),
  • itching, or
  • skin rash.

Tell your doctor if you have serious side effects of Lotensin including:

  • fainting,
  • changes in urine output,
  • blistering red skin rash,
  • unusual tiredness,
  • easy bruising or bleeding,
  • serious flu-like symptoms,
  • swelling or rapid weight gain,
  • fever, chills, body aches, flu symptoms,
  • pale or yellowed skin,
  • dark colored urine,
  • confusion or weakness,
  • purple or red pinpoint spots under your skin,
  • yellowing of the skin or eyes (jaundice),
  • high potassium (slow heart rate, weak pulse, muscle weakness, tingly feeling), or
  • severe skin reaction (fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads [especially in the face or upper body] and causes blistering and peeling).

Dosage for Lotensin

Lotensin is supplied as tablets containing strengths of 5, 10, 20, and 40 mg of benazepril hydrochloride for oral administration. The usual starting dose is 10 mg per day.

What Drugs, Substances, or Supplements Interact with Lotensin?

Lotensin may interact with salt substitutes or potassium supplements, other blood pressure medications, gold injections, insulin or oral diabetes medications, lithium, or diuretics (water pills). Tell your doctor all medications and supplements you use.

Lotensin During Pregnancy or Breastfeeding

Lotensin should not be used in pregnant females as it may damage the fetus. The drug has been found in breast milk so use in breastfeeding women must be weighed against the possible harm to the infant. Lotensin is not recommended for children under 6 years old. However, doses of Lotensin between 0.1 and 0.6 mg/kg once daily have been studied, and doses greater than 0.1 mg/kg were shown to reduce blood pressure. Consequently, the recommended starting dose of Lotensin in children 6 years and older is 0.2 mg/kg once per day as monotherapy. Doses above 0.6 mg/kg have not been studied in children 6 years and older.

Additional Information

Our Lotensin Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Salt and sodium are the same. See Answer
Lotensin Consumer Information

2 pharmacies near 20147 have coupons for Lotensin (Brand Names:Lotensin for 5MG)


with free coupon

View Coupon
Wegmans Food Markets Inc
Wegmans Food Markets Inc

with free coupon

View Coupon

Get emergency medical help if you have signs of an allergic reaction (hives, severe stomach pain, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • little or no urinating;
  • high potassium--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement; or
  • liver problems--stomach pain (upper right side), loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • headache; or
  • cough.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Lotensin (Benazepril)


How to Lower Blood Pressure: Exercise Tips See Slideshow
Lotensin Professional Information


Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in practice.

Lotensin has been evaluated for safety in over 6000 patients with hypertension; over 700 of these patients were treated for at least one year. The overall incidence of reported adverse events was similar in Lotensin and placebo patients.

The reported side effects were generally mild and transient, and there was no relation between side effects and age, duration of therapy, or total dosage within the range of 2 to 80 mg.

Discontinuation of therapy because of a side effect was required in approximately 5% of U.S. patients treated with Lotensin and in 3% of patients treated with placebo. The most common reasons for discontinuation were headache (0.6%) and cough (0.5%).

Adverse reactions seen in at least 1% greater frequency in patients treated with Lotensin than placebo were headache (6% vs. 4%), dizziness (4% vs. 2%), somnolence (2% vs. 0%) and postural dizziness (2% vs. 0%).

Adverse reactions reported in controlled clinical trials (less than 1% more on benazepril than on placebo), and rarer events seen in post-marketing experience, include the following (in some, a causal relationship to drug use is uncertain):

Dermatologic: Stevens-Johnson syndrome, pemphigus, apparent hypersensitivity reactions (manifested by dermatitis, pruritus, or rash), photosensitivity, and flushing.

Gastrointestinal: Nausea, pancreatitis, constipation, gastritis, vomiting, and melena.

Hematologic: Thrombocytopenia and hemolytic anemia.

Neurologic/Psychiatric: Anxiety, decreased libido, hypertonia, insomnia, nervousness, and paresthesia.

Other: Fatigue, asthma, bronchitis, dyspnea, sinusitis, urinary tract infection, frequent urination, infection, arthritis, impotence, alopecia, arthralgia, myalgia, asthenia, sweating.

Laboratory Abnormalities

Elevations of uric acid, blood glucose, serum bilirubin, and liver enzymes [see WARNINGS AND PRECAUTIONS] have been reported, as have incidents of hyponatremia, electrocardiographic changes, eosinophilia, and proteinuria.

Read the entire FDA prescribing information for Lotensin (Benazepril)

© Lotensin Patient Information is supplied by Cerner Multum, Inc. and Lotensin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors