Lotrisone Side Effects Center

Last updated on RxList: 4/26/2022
Lotrisone Side Effects Center

What Is Lotrisone?

Lotrisone (clotrimazole and betamethasone) is a combination of an antifungal antibiotic and a topical steroid cream or lotion used to treat or prevent fungal infections of the skin such as athlete's foot, jock itch, and ringworm, and to reduce itching, swelling, and redness of the skin.

What Are Side Effects of Lotrisone?

Side effects of Lotrisone include:

  • itching,
  • skin irritation,
  • dry skin,
  • changes in skin color,
  • increased acne,
  • burning/tingling/stinging skin, or
  • scarring or thinning of the skin.

Dosage for Lotrisone

Apply a thin film dose of Lotrisone cream into the affected skin areas twice a day for one week.

What Drugs, Substances, or Supplements Interact with Lotrisone?

Lotrisone may interact with other drugs. Tell your doctor all medications and supplements you use.

Lotrisone During Pregnancy or Breastfeeding

There are no adequate studies in pregnant women of the teratogenic effects of topically applied corticosteroids, so this drug should be used during pregnancy only if the potential benefit justifies the potential risk. It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Consult your doctor before breastfeeding.

Additional Information

Our Lotrisone Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Ringworm is caused by a fungus. See Answer
Lotrisone Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • worsening of your skin condition;
  • redness, warmth, swelling, oozing, or severe irritation of any treated skin;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor; or
  • possible signs of absorbing this medicine through your skin--weight gain (especially in your face or your upper back and torso), slow wound healing, thinning or discolored skin, increased body hair, muscle weakness, nausea, diarrhea, tiredness, mood changes, menstrual changes, sexual changes.

Common side effects may include:

  • numbness, tingling, or stinging;
  • skin dryness or rash;
  • swelling; or
  • new infections.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Lotrisone (Clotrimazole and Betamethasone)

SLIDESHOW

Rosacea, Acne, Shingles, Covid-19 Rashes: Common Adult Skin Diseases See Slideshow
Lotrisone Professional Information

SIDE EFFECTS

Clinical Trial Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

In clinical trials common adverse reaction reported for LOTRISONE cream was paresthesia in 1.9% of patients. Adverse reactions reported at a frequency < 1% included rash, edema, and secondary infection.

Postmarketing Experience

Because adverse reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.

The following local adverse reactions have been reported with topical corticosteroids: itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, skin atrophy, striae, miliaria, capillary fragility (ecchymoses), telangiectasia, and sensitization (local reactions upon repeated application of product).

Ophthalmic adverse reactions of blurred vision, cataracts, glaucoma, increased intraocular pressure, and central serous chorioretinopathy have been reported with the use of topical corticosteroids, including topical betamethasone products.

Adverse reactions reported with the use of clotrimazole are: erythema, stinging, blistering, peeling, edema, pruritus, urticaria, and general irritation of the skin.

Read the entire FDA prescribing information for Lotrisone (Clotrimazole and Betamethasone)

© Lotrisone Patient Information is supplied by Cerner Multum, Inc. and Lotrisone Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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