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Lovenox vs. Eliquis

Medical and Pharmacy Editor:

Are Eliquis and Lovenox the Same Thing?

Lovenox (enoxaparin sodium) and Eliquis (apixaban) are blood thinners (anticoagulants) used to prevent blood clots and reduce the risk of stroke and systemic embolism.

Lovenox is also used to prevent blood vessel complications in people with certain types of angina (chest pain) or heart attacks called non-Q-wave myocardial infarction or ST-segment elevation myocardial infarction.

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What Are Possible Side Effects of Lovenox?

Common side effects of Lovenox include:

  • nausea,
  • diarrhea,
  • fever,
  • swelling in your hands or feet, or
  • injection site reactions (swelling, pain, bruising, or redness).

What Are Possible Side Effects of Eliquis?

Common side effects of Eliquis include:

  • skin rash,
  • allergic reactions,
  • fainting, nausea, and
  • anemia.

Tell your doctor if you have serious side effects of Eliquis including easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), bleeding from wounds or needle injections, any bleeding that will not stop; heavy menstrual periods; headache, dizziness, weakness, feeling like you might pass out; red, pink, or brown urine; black or bloody stools, coughing up blood or vomit that looks like coffee grounds; numbness, tingling, or muscle weakness (especially in your legs and feet); or loss of movement in any part of your body.

What is Eliquis?

Eliquis (apixaban) is an anticoagulant (blood thinner) that reduces blood clotting and reduces the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation.

What Drugs Interact With Lovenox?

Lovenox may interact with aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), and other medicines to prevent blood clots.

Lovenox may also interact with dextran.

What Drugs Interact With Eliquis?

Eliquis may interact with blood thinners and heparin, antibiotics, antidepressants, antifungals, antithrombotics, bone marrow stimulants, bosentan, conivaptan, cyclosporine, dextran, heart or blood pressure medications, hepatitis C medications, HIV/AIDS medications, imatinib, isoniazid, nefazodone, nonsteroidal anti-inflammatory drugs (NSAIDs), rifabutin, rifampin, rifapentine, salicylates (such as aspirin, Pepto-Bismol, and others), seizure medications, St. John's wort, thrombopoietic growth factors, or vasodilators.

How Should Lovenox Be Taken?

The recommended dose of Lovenox for most patients is 5 mg taken orally twice daily.

The recommended dose of Lovenox is 2.5 mg twice daily in patients with at least two of the following characteristics:

  • age ≥ 80 years
  • body weight ≤ 60 kg
  • serum creatinine ≥ 1.5 mg/dL

How Should Eliquis Be Taken?

The recommended dose of Eliquis for most patients is 5 mg taken orally twice daily.

Reviewed on 7/11/2018

References:

Sanofi-aventis. Lovenox Product Information.

https://www.lovenox.com/

Eliquis Product Information.

http://www.eliquis.com/

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