Low vision: A visual impairment, not corrected by standard glasses, contact lenses, medicine, or surgery, that interferes with the ability to perform everyday activities. Low vision can be a result of eye conditions such as nystagmus, intraocular trauma, inflammation or retinal conditions such as diabetic retinopathy or age-related macular degeneration (AME). Low vision primarily affects people over age 65. High risk populations include Hispanics and African Americans, who are likely to develop low vision at an earlier age. While lost vision usually cannot be restored, many people can learn to make the most of the vision that remains.