Lymphazurin Side Effects Center

Last updated on RxList: 3/10/2022
Lymphazurin Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Lymphazurin?

Lymphazurin 1% (Isosulfan Blue) Aqueous Solution is a contrast agent used to delineate lymphatic vessels draining in the region of injection. Lymphazurin 1% is available in generic form.

What Are Side Effects of Lymphazurin?

Common side effects of Lymphazurin 1% include:

  • hypersensitivity near the injection site,
  • a temporary blue coloring to the skin,
  • minor allergic reactions such as itching and hives, or
  • serious allergic reactions including respiratory distress and shock.

Dosage for Lymphazurin/h4>

Lymphazurin 1% is administered subcutaneously, one-half (1/2) ml into three (3) interdigital spaces (spaces between fingers or toes) of each extremity per study. A maximum dose of 3 ml (30 mg) is injected.

What Drugs, Substances, or Supplements Interact with Lymphazurin?

Lymphazurin may interact with other drugs. Tell your doctor all medications and supplements you use.

Lymphazurin During Pregnancy or Breastfeeding

During pregnancy, Lymphazurin should be used only if prescribed. It is unknown if Lymphazurin passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Lymphazurin 1% (Isosulfan Blue) Aqueous Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Lymphazurin Professional Information


Postmarketing Experience

Hypersensitivity Reactions: Case series report an overall incidence of hypersensitivity reactions in approximately 2% of patients. Life-threatening anaphylactic reactions have occurred. Manifestations include respiratory distress, shock, angioedema, urticaria, pruritus. A death has been reported following administration of a similar compound employed to estimate the depth of a severe burn. Reactions are more likely to occur in patients with a personal or family history of bronchial asthma, significant allergies, drug reactions or previous reactions to triphenylmethane dyes [see WARNINGS AND PRECAUTIONS].

Laboratory tests: Lymphazurin 1% interferes with measurements of oxygen saturation by pulse oximetry and of methemoglobin by gas analyzer [see WARNINGS AND PRECAUTIONS].

Skin: transient or long-term (tattooing) blue coloration.

Read the entire FDA prescribing information for Lymphazurin (Isosulfan Blue)


Digestive Disorders: Common Misconceptions See Slideshow

© Lymphazurin Patient Information is supplied by Cerner Multum, Inc. and Lymphazurin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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