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Macrobid vs. Macrodantin

Medical and Pharmacy Editor:

Are Macrobid and Macrodantin the Same Thing?

Macrobid (nitrofurantoin monohydrate/macrocrystals) and Macrodantin (nitrofurantoin) are antibiotics used to treat urinary tract and bladder infections.

A difference is that Macrobid is taken twice daily, and Macrodantin is taken four times a day.

What Are Possible Side Effects of Macrobid?

Common side effects of Macrobid include:

  • nausea,
  • vomiting,
  • upset stomach,
  • diarrhea,
  • rust-colored or brownish urine,
  • vaginal itching or discharge,
  • headaches, and
  • gas.

Tell your doctor if you experience serious side effects of Macrobid including:

  • bloody or watery diarrhea,
  • sudden chest pain,
  • shortness of breath,
  • cough,
  • fever or chills,
  • numbness or tingling in the hands or feet, or
  • easy bruising.

What Are Possible Side Effects of Macrodantin?

Common side effects of Macrodantin include:

  • headache,
  • itching,
  • rash,
  • nausea,
  • upset stomach,
  • vomiting,
  • loss of appetite,
  • diarrhea,
  • rust-colored or brownish urine, or
  • vaginal itching or discharge.

What is Macrobid?

Macrobid (nitrofurantoin monohydrate/macrocrystals) is an antibacterial drug used to treat urinary tract and bladder infections caused by Escherichia coli or Staphyloccocus saprophyticus strains of bacteria that are sensitive to this drug. Macrobid is available as a generic. Macrobid should not be used for pyelonephritis (kidney infections) or other deep tissue infections such as perinephric abscesses.

What is Macrodantin?

Macrodantin (nitrofurantoin) is an antibiotic prescribed to treat or prevent urinary tract infections. Macrodantin is available in generic form.

What Drugs Interact With Macrobid?

Macrobid may also interact with magnesium salicylate or choline magnesium salicylate.

What Drugs Interact With Macrodantin?

Macrodantin may interact with antacids, magnesium salicylate, choline magnesium salicylate, or probenecid. Tell your doctor all medications and supplements you use.

How Should Macrobid Be Taken?

Macrobid is available in 100 mg tablets for use in children under 12 years old and adults. Macrobid may interact with magnesium salicylate, choline magnesium salicylate, and probenecid or other gout medications.

How Should Macrodantin Be Taken?

Macrodantin should be given with food to improve drug absorption and, in some patients, tolerance. Adults should take 50-100 mg four times a day-the lower dosage level is recommended for uncomplicated urinary tract infections.

Reviewed on 8/9/2018


DailyMed. Macrobid Prescribing Information.

DailyMed. Macrodantin Product Information.

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