Definition of Major anomaly

Reviewed on 6/3/2021

Major anomaly: An unusual anatomic feature that is of serious medical or cosmetic consequence to the patient. For example, a major anomaly might be a cleft lip and palate.

By contrast, a minor anomaly is an unusual anatomic feature not of serious medical or cosmetic consequence to the patient. For example, a minor anomaly might be curvature of the second toe so it overlaps the third toe.

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