Definition of Malignant giant cell tumor

Reviewed on 3/29/2021

Malignant giant cell tumor: A type of bone tumor that is characterized by massive destruction of bone near the end (epiphysis) of a long bone and causes pain and restricts movement. The most common site of malignant giant cell tumor is the knee. Diagnosis is made by examining a sample of the affected area. Treatment involves excising the affected area, usually followed by chemotherapy or radiation.

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