Mannitol IV

Last updated on RxList: 8/11/2020
Mannitol IV Side Effects Center

What Is Mannitol IV?

Mannitol I.V. (mannitol injection) is a diuretic used to increase urine production, and to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). Mannitol I.V. is available in generic form.

What Are Side Effects of Mannitol IV?

Common side effects of Mannitol I.V. include:

Dosage for Mannitol IV

The usual adult dosage of Mannitol ranges from 50 to 200 g in a 24-hour period, but in most instances an adequate response will be achieved at a dosage of approximately 100 g/24 hours.

What Drugs, Substances, or Supplements Interact with Mannitol IV?

Mannitol may interact with other drugs. Tell your doctor all medications and supplements you use.

Mannitol IV During Pregnancy and Breastfeeding

During pregnancy, Mannitol should be used only if prescribed. Consult your doctor before breastfeeding.

Additional Information

Our Mannitol I.V. (mannitol injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Mannitol IV Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers right away if you have:

  • swelling in your hands or lower legs, rapid weight gain;
  • little or no urination;
  • shortness of breath (even while lying down);
  • wheezing, gasping for breath, cough with foamy mucus;
  • chest pain, fast heartbeats;
  • headache, or feeling like you might pass out;
  • a seizure;
  • painful or difficult urination;
  • pain, bruising, irritation, or skin changes where the injection was given;
  • dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or
  • signs of an electrolyte imbalance--increased thirst or urination, confusion, vomiting, constipation, muscle pain or weakness, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling.

Common side effects may include:

  • increased urination;
  • nausea, vomiting;
  • fever, chills, headache, runny nose;
  • chest pain;
  • rash; or
  • dizziness, blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Mannitol IV (Mannitol Injection)


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Mannitol IV Professional Information


Adverse reactions more commonly reported during or after the infusion of mannitol (mannitol (mannitol injection) injection) include: Pulmonary congestion, fluid and electrolyte imbalance, acidosis, electrolyte loss, dryness of mouth, thirst, marked diuresis, urinary retention, edema, headache, blurred vision, convulsions, nausea, vomiting, rhinitis, arm pain, skin necrosis, thrombophlebitis, chills, dizziness, urticaria, dehydration, hypotension, tachycardia, fever and angina-like chest pains.

Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.

If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.

Read the entire FDA prescribing information for Mannitol IV (Mannitol Injection)

© Mannitol IV Patient Information is supplied by Cerner Multum, Inc. and Mannitol IV Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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