Medical Editor: John P. Cunha, DO, FACOEP
What Is Mannitol IV?
Mannitol I.V. (mannitol injection) is a diuretic used to increase urine production, and to treat or prevent medical conditions that are caused by an increase in body fluids/water (e.g., cerebral edema, glaucoma, kidney failure). Mannitol I.V. is available in generic form.
What Are Side Effects of Mannitol IV?
Common side effects of Mannitol I.V. include:
- dry mouth,
- blurred vision,
- runny nose,
- arm pain,
- low blood pressure (hypotension),
- irregular heart beat,
- electrolyte imbalance, and
- irritation/pain/swelling at the injection site.
Dosage for Mannitol IV
The usual adult dosage of Mannitol ranges from 50 to 200 g in a 24-hour period, but in most instances an adequate response will be achieved at a dosage of approximately 100 g/24 hours.
What Drugs, Substances, or Supplements Interact with Mannitol IV?
Mannitol may interact with other drugs. Tell your doctor all medications and supplements you use.
Mannitol IV During Pregnancy and Breastfeeding
During pregnancy, Mannitol should be used only if prescribed. Consult your doctor before breastfeeding.
Our Mannitol I.V. (mannitol injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Adverse reactions more commonly reported during or after the infusion of mannitol (mannitol (mannitol injection) injection) include: Pulmonary congestion, fluid and electrolyte imbalance, acidosis, electrolyte loss, dryness of mouth, thirst, marked diuresis, urinary retention, edema, headache, blurred vision, convulsions, nausea, vomiting, rhinitis, arm pain, skin necrosis, thrombophlebitis, chills, dizziness, urticaria, dehydration, hypotension, tachycardia, fever and angina-like chest pains.
Reactions which may occur because of the solution or the technique of administration include febrile response, infection at the site of injection, venous thrombosis or phlebitis extending from the site of injection, extravasation and hypervolemia.
If an adverse reaction does occur, discontinue the infusion, evaluate the patient, institute appropriate therapeutic countermeasures and save the remainder of the fluid for examination if deemed necessary.
Read the entire FDA prescribing information for Mannitol IV (Mannitol Injection)