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Maxitrol

Last reviewed on RxList: 1/2/2018
Maxitrol Side Effects Center

Last reviewed on RxList 1/2/2018

Maxitrol (neomycin and polymyxin B sulfates and dexamethasone) Ophthalmic Suspension Sterile is a combination of two antibiotics and a steroid used to treat bacterial infections of the eyes. Maxitrol is available in generic form. Common side effects of Maxitrol include:

  • stinging/burning of the eyes for 1 to 2 minutes when Maxitrol is applied,
  • irritation,
  • itching,
  • redness,
  • blurred vision,
  • eyelid itching,
  • eyelid swelling, or
  • sensitivity to light.
Serious side effects are generally not expected with Maxitrol. Use of Maxitrol for prolonged or repeated periods may result in a new fungal eye infection and may increase your risk for other eye problems (e.g., glaucoma, cataracts, delayed wound healing). Do not use Maxitrol for longer than prescribed. Tell your doctor if you experience unlikely but serious side effects of Maxitrol including new or worsening eye symptoms (e.g., discharge, swelling, redness), vision problems, or eye pain.

Dosing of Maxitrol: One to two drops in the conjunctival sac(s). In severe disease, drops may be used hourly, being tapered to discontinuation as the inflammation subsides. In mild disease, drops may be used up to four to six times daily. Avoid other eye medications unless approved by your doctor. Before using Maxitrol, tell your doctor if you are taking an oral steroid medication such as prednisone (Deltasone, Orasone, others). Other drugs may also interact with Maxitrol. Talk to your doctor before taking any prescription or over-the-counter medicines. During pregnancy, Maxitrol should be used only when prescribed. It is not known if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Maxitrol (neomycin and polymyxin B sulfates and dexamethasone) Ophthalmic Suspension Sterile Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

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Maxitrol Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);
  • pain behind your eyes, sudden vision changes; or
  • a wound that will not heal.

Common side effects may include:

  • blurred vision; or
  • mild eye irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Maxitrol (Neomycin, Polymyxin B and Dexamethasone Ophthalmic)

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Maxitrol Professional Information

SIDE EFFECTS

Adverse reactions have occurred with steroid/anti-infective combination drugs which can be attributed to the steroid component, the anti-infective component, or the combination. Exact incidence figures are not available since no denominator of treated patients is available.

Reactions occurring most often from the presence of the anti-infective ingredient are allergic sensitizations. The reactions due to the steroid component are: elevation of IOP with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing.

Secondary Infection

The development of secondary infection has occurred after use of combinations containing steroids and antimicrobials. Fungal infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroid. The possibility of fungal invasion must be considered in any persistent corneal ulceration where steroid treatment has been used. Keratitis, conjunctivitis, corneal ulcers, and conjunctival hyperemia have occasionally been reported following use of steroids. Secondary bacterial ocular infection following suppression of host responses also occurs.

Additional adverse reactions identified from post marketing use include ulcerative keratitis, headache, and Stevens-Johnson syndrome.

Read the entire FDA prescribing information for Maxitrol (Neomycin, Polymyxin B and Dexamethasone Ophthalmic)

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© Maxitrol Patient Information is supplied by Cerner Multum, Inc. and Maxitrol Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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