MDP-25 Side Effects Center

Last updated on RxList: 4/7/2022
MDP-25 Side Effects Center

What Is MDP-25?

MDP-25 (kit for the preparation of technetium Tc 99m medronate injection) may be used as a bone imaging agent to delineate areas of altered osteogenesis.

What Are Side Effects of MDP-25?

Side effects of MDP-25 include:

Dosage for MDP-25

The recommended adult dose of MDP-25, after reconstitution with oxidant-free sodium pertechnetate Tc 99m, is 370 to 740 megabecquerels (10 to 20 millicuries [200 μCi/kg]) by slow intravenous injection over a period of 30 seconds. Optimum scanning time is 1 to 4 hours post-injection.

MDP-25 In Children

Safety and effectiveness of MDP-25 in pediatric patients have not been established.

What Drugs, Substances, or Supplements Interact with MDP-25?

MDP-25 may interact with other medicines.

Tell your doctor all medications and supplements you use.

MDP-25 During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using MDP-25; it is unknown how it might affect a fetus. Ideally, examinations using radiopharmaceuticals, especially those that are elective in nature, of a woman of childbearing capability should be performed during the first few (approximately 10) days following the onset of menses. MDP-25 passes into breast milk and formula feedings should be substituted for breastfeeding.

Additional Information

Our MDP-25 (kit for the preparation of technetium Tc 99m medronate injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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MDP-25 Professional Information


Several cases of allergic dermatological reactions have been reported in association with the use of Technetium Tc 99m Medronate.

Several reactions have also been reported in association with other radiopharmaceuticals of the diphosphonate class, particularly Technetium Tc 99m Medronate. These are usually hypersensitivity reactions characterized by itching, various skin rashes, hypotension, chills, nausea, fever, and vomiting. One death secondary to cardiac arrhythmia following the administration of Technetium Tc 99m Medronate has been reported. In addition, one case of cardiac arrest in a patient also undergoing pulmonary function testing one and one-half hours after the performance of a bone scan using Technetium Tc 99m Medronate has been reported.

Read the entire FDA prescribing information for MDP-25 (Kit for the Preparation of Technetium Tc 99m Medronate Injection)


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© MDP-25 Patient Information is supplied by Cerner Multum, Inc. and MDP-25 Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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