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Medrol (methylprednisolone) vs. Prednisone

Are Prednisone and Medrol the Same Thing?

Medrol (methylprednisolone) and prednisone are glucocorticoids indicated to treat or manage many conditions, endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, allergies, ophthalmic (eye) diseases, respiratory diseases, hematologic disorders, neoplastic diseases (cancers), edematous states, gastrointestinal diseases, and others.

Brand names for prednisone include Deltasone, Rayos, and Prednisone Intensol.

What Are Possible Side Effects of Prednisone?

Common side effects of Prednisone include:

Tell your doctor if you experience serious side effects of prednisone including

What Are Possible Side Effects of Medrol?

Common side effects of Medrol include:

  • skin problems (acne, dry and thinning skin, easy bruising or discoloration),
  • slow wound healing,
  • changes in the shape or location of body fat (especially in the neck, face, arms, legs, breasts, and waist),
  • nausea,
  • stomach pain,
  • bloating,
  • headache,
  • dizziness,
  • spinning sensation,
  • sleep problems (insomnia),
  • increased sweating, and
  • mood changes.

Serious side effects of Medrol include emergency medical conditions such as:

What is Prednisone?

Prednisone is a glucocorticoid indicated to treat or manage many conditions, including endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, allergies, ophthalmic (eye) diseases, respiratory diseases, hematologic disorders, neoplastic diseases (cancers), edematous states, and gastrointestinal diseases.

What is Medrol?

Medrol (methylprednisolone) is a glucocorticoid (adrenocortical steroid) that can depress the immune response and inflammation and is used in diseases ranging from rheumatologic, hematologic, endocrine, dermatologic, immunologic, allergic, and ophthalmologic to many others.

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What Drugs Interact With Prednisone?

Prednisone may interact with diuretics (water pills), rifampin, or vaccines.

Prednisone may also interact with macrolide antibiotics, anticholinesterase, anticoagulants, antidiabetic drugs, isoniazid, bupropion, cholestyramine, cyclosporine, digitalis glycosides, estrogens (including oral contraceptives), fluoroquinolones, barbiturates, phenytoin, carbamazepine, azole antifungals, ritonavir, indinavir, nonsteroidal anti-inflammatory drugs (NSAIDs), phenytoin, quetiapine, allergy skin tests, and thalidomide.

What Drugs Interact With Medrol?

Medrol may interact with diuretics (water pills), rifampin, or vaccines.

Medrol may also interact with aspirin (taken on a daily basis or at high doses), blood thinner, cyclosporine, insulin or oral diabetes medications, ketoconazole, or seizure medications.

How Should Prednisone Be Taken?

The initial dosage of prednisone may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated.

How Should Medrol Be Taken?

Medrol is available as 2, 4, 8, 16 or 32 mg strength tablets. Dosages are extremely variable and are based on what diseases are being treated.

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You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

RxList. Prednisone Side Effects Drug Center.
https://www.rxlist.com/prednisone-side-effects-drug-center.htm
RxList. Medrol Side Effects Drug Center.
https://www.rxlist.com/medrol-side-effects-drug-center.htm

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