Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.

Medrol (methylprednisolone) vs. Prednisone

  • Medical and Pharmacy Editor: John P. Cunha, DO, FACOEP
    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, FACOEP

    John P. Cunha, DO, is a U.S. board-certified Emergency Medicine Physician. Dr. Cunha's educational background includes a BS in Biology from Rutgers, the State University of New Jersey, and a DO from the Kansas City University of Medicine and Biosciences in Kansas City, MO. He completed residency training in Emergency Medicine at Newark Beth Israel Medical Center in Newark, New Jersey.

Are Prednisone and Medrol the Same Thing?

Medrol (methylprednisolone) and prednisone are glucocorticoids indicated to treat or manage many conditions, endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, allergies, ophthalmic (eye) diseases, respiratory diseases, hematologic disorders, neoplastic diseases (cancers), edematous states, gastrointestinal diseases, and others.

Brand names for prednisone include Deltasone, Rayos, and Prednisone Intensol.

What Are Possible Side Effects of Prednisone?

Common side effects of Prednisone include:

  • headache,
  • nausea,
  • vomiting,
  • acne, thinning skin,
  • weight gain,
  • restlessness, and
  • trouble sleeping.

Tell your doctor if you experience serious side effects of prednisone including

  • severe allergic reactions (skin rash, itching, hives, swelling of your lips/face/tongue),
  • mood changes or depression,
  • eye pain or vision changes,
  • fever,
  • cough,
  • sore throat,
  • difficulty urinating, or
  • high blood sugar (increased thirst, increased urination, confusion, or swelling of the ankles and feet).

What Are Possible Side Effects of Medrol?

Common side effects of Medrol include:

  • skin problems (acne, dry and thinning skin, easy bruising or discoloration),
  • slow wound healing,
  • changes in the shape or location of body fat (especially in the neck, face, arms, legs, breasts, and waist),
  • nausea,
  • stomach pain,
  • bloating,
  • headache,
  • dizziness,
  • spinning sensation,
  • sleep problems (insomnia),
  • increased sweating, and
  • mood changes.

Serious side effects of Medrol include emergency medical conditions such as:

  • low potassium,
  • bloody vomit,
  • bloody or tarry stools,
  • high blood pressure,
  • seizures,
  • chest pains,
  • mental status changes,
  • pancreatitis,
  • vision problems, and
  • shortness of breath with swelling.

What is Prednisone?

Prednisone is a glucocorticoid indicated to treat or manage many conditions, including endocrine disorders, rheumatic disorders, collagen diseases, dermatologic diseases, allergies, ophthalmic (eye) diseases, respiratory diseases, hematologic disorders, neoplastic diseases (cancers), edematous states, and gastrointestinal diseases.

What is Medrol?

Medrol (methylprednisolone) is a glucocorticoid (adrenocortical steroid) that can depress the immune response and inflammation and is used in diseases ranging from rheumatologic, hematologic, endocrine, dermatologic, immunologic, allergic, and ophthalmologic to many others.

What Drugs Interact With Prednisone?

Prednisone may interact with diuretics (water pills), rifampin, or vaccines.

Prednisone may also interact with macrolide antibiotics, anticholinesterase, anticoagulants, antidiabetic drugs, isoniazid, bupropion, cholestyramine, cyclosporine, digitalis glycosides, estrogens (including oral contraceptives), fluoroquinolones, barbiturates, phenytoin, carbamazepine, azole antifungals, ritonavir, indinavir, nonsteroidal anti-inflammatory drugs (NSAIDs), phenytoin, quetiapine, allergy skin tests, and thalidomide.

What Drugs Interact With Medrol?

Medrol may interact with diuretics (water pills), rifampin, or vaccines.

Medrol may also interact with aspirin (taken on a daily basis or at high doses), blood thinner, cyclosporine, insulin or oral diabetes medications, ketoconazole, or seizure medications.

How Should Prednisone Be Taken?

The initial dosage of prednisone may vary from 5 mg to 60 mg per day, depending on the specific disease entity being treated.

How Should Medrol Be Taken?

Medrol is available as 2, 4, 8, 16 or 32 mg strength tablets. Dosages are extremely variable and are based on what diseases are being treated.

From WebMD Logo

Reviewed on 2/28/2018

References:
RxList. Prednisone Side Effects Drug Center.
https://www.rxlist.com/prednisone-side-effects-drug-center.htm
RxList. Medrol Side Effects Drug Center.
https://www.rxlist.com/medrol-side-effects-drug-center.htm

CONTINUE SCROLLING FOR RELATED SLIDESHOW

Health Solutions From Our Sponsors