Medical Editor: John P. Cunha, DO, FACOEP
- decreased appetite,
- changes in taste,
- increased sensitivity of the skin to sunlight,
- worsening gout,
- loss of blood sugar control (if you are diabetic),
- ringing in your ears (tinnitus) or hearing problems,
- changes in vision,
- tingling feeling in the extremities,
- general feeling of being unwell (malaise), and
- increased urination.
The effective therapeutic dose of methazolamide varies from 50mg to 100mg, 2 or 3 times daily. The drug may be used at the same time as miotic and osmotic agents. Methazolamide may interact with cyclosporine, primidone, diflunisal, aspirin or other salicylates, or lithium. Tell your doctor all medications and supplements you use. During pregnancy, methazolamide should be taken only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Our methazolamide Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
- blood in urine or stools;
- a seizure (convulsions);
- loss of movement in any part of your body;
- a blood cell disorder--sudden weakness or ill feeling, fever, chills, sore throat, mouth sores, pale skin, feeling tired or short of breath, rapid heart rate, nosebleeds, bleeding gums;
- liver problems--nausea, upper stomach pain or swelling, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- signs of metabolic acidosis--confusion, vomiting, lack of energy, irregular heartbeats;
- signs of a kidney stone--pain in your side or lower back, blood in your urine, painful or difficult urination; or
- severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common side effects may include:
- nausea, vomiting, loss of appetite, diarrhea;
- numbness or tingling, especially in your arms and legs;
- drowsiness, confusion;
- hearing problems, ringing in your ears;
- increased urination; or
- altered sense of taste.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Methazolamide (Methazolamide)
Adverse reactions, occurring most often early in therapy, include paresthesias, particularly a "tingling" feeling in the extremities; hearing dysfunction or tinnitus; fatigue; malaise; loss of appetite; taste alteration; gastrointestinal disturbances such as nausea, vomiting and diarrhea; polyuria; and occasional instances of drowsiness and confusion.
Metabolic acidosis and electrolyte imbalance may occur.
Transient myopia has been reported. This condition invariably subsides upon diminution or discontinuance of the medication.
Other occasional adverse reactions include urticaria, melena, hematuria, glycosuria, hepatic insufficiency, flaccid paralysis, photosensitivity, convulsions, and, rarely, crystalluria and renal calculi. Also see PRECAUTIONS: Information for Patients for possible reactions common to sulfonamide derivatives. Fatalities have occurred, although rarely, due to severe reactions to sulfonamides including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias (see WARNINGS).
Read the entire FDA prescribing information for Methazolamide (Methazolamide)
© Methazolamide Patient Information is supplied by Cerner Multum, Inc. and Methazolamide Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.