Medical Editor: John P. Cunha, DO, FACOEP
Microzide (hydrochlorothiazide) is a diuretic (water pill) prescribed for lowering blood pressure (hypertension) and accumulation of fluid (edema). Microzide is available as a generic drug. Common side effects of Microzide include:
- low blood pressure,
- light sensitivity,
- blurred vision,
- abdominal or stomach pain,
- electrolyte disturbances,
- yellow skin or eyes (jaundice),
- severe allergic reaction (anaphylaxis), and
Tell your doctor if you have serious side effects of Microzide including:
- decrease in vision, or
- eye pain.
Microzide dose ranges from 12.5 to 100 mg/day depending on the condition that is being treated. Microzide may interact with other medicines that make you lightheaded (such as cold medicines, pain medications, muscle relaxers, and medicines for seizures, depression or anxiety), lithium, digoxin, cholestyramine, colestipol, steroids, other blood pressure medication, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as aspirin, ibuprofen, naproxen, and others), or insulin or oral diabetes medications. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Microzide. Microzide is not expected to be harmful to a fetus. Microzide can pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.
Our Microzide Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using this medication and call your doctor at once if you have a serious side effect such as:
- eye pain, vision problems;
- dry mouth, thirst, nausea, vomiting;
- feeling weak, drowsy, restless, or light-headed;
- fast or uneven heartbeat;
- muscle pain or weakness;
- numbness or tingly feeling;
- a red, blistering, peeling skin rash; or
- nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Less serious side effects may include:
- mild stomach pain;
- constipation; or
- blurred vision.
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
Read the entire detailed patient monograph for Microzide (Hydrochlorothiazide Capsule)
The adverse reactions associated with hydrochlorothiazide have been shown to be dose related. In controlled clinical trials, the adverse events reported with doses of 12.5 mg hydrochlorothiazide once daily were comparable to placebo. The following adverse reactions have been reported for doses of hydrochlorothiazide 25 mg and greater and, within each category, are listed in the order of decreasing severity.
Body as a whole: Weakness.
Hypersensitivity: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, fever, urticaria, rash, purpura.
Musculoskeletal: Muscle spasm.
Renal: Renal failure, renal dysfunction, interstitial nephritis (see WARNINGS).
Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn.
Read the entire FDA prescribing information for Microzide (Hydrochlorothiazide Capsule)
© Microzide Patient Information is supplied by Cerner Multum, Inc. and Microzide Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.