Microzide

Last updated on RxList: 4/23/2021
Microzide Side Effects Center

What Is Microzide?

Microzide (hydrochlorothiazide) is a diuretic (water pill) prescribed for lowering blood pressure (hypertension) and accumulation of fluid (edema). Microzide is available as a generic drug.

What Are Side Effects of Microzide?

Common side effects of Microzide include:

Tell your doctor if you have serious side effects of Microzide including:

Dosage for Microzide

Microzide dose ranges from 12.5 to 100 mg/day depending on the condition that is being treated.

What Drugs, Substances, or Supplements Interact with Microzide?

Microzide may interact with other medicines that make you lightheaded (such as cold medicines, pain medications, muscle relaxers, and medicines for seizures, depression or anxiety), lithium, digoxin, cholestyramine, colestipol, steroids, other blood pressure medication, nonsteroidal anti-inflammatory drugs (NSAIDs) (such as aspirin, ibuprofen, naproxen, and others), or insulin or oral diabetes medications. Tell your doctor all medications and supplements you use.

Microzide During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant during treatment with Microzide. Microzide is not expected to be harmful to a fetus. Microzide can pass into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

Additional Information

Our Microzide Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Salt and sodium are the same. See Answer
Microzide Consumer Information

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Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Call your doctor at once if you have:

  • a light-headed feeling;
  • eye pain, vision problems;
  • jaundice (yellowing of the skin or eyes);
  • pale skin, easy bruising, unusual bleeding (nose, mouth, vagina, or rectum);
  • shortness of breath, wheezing, cough with foamy mucus, chest pain;
  • dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or
  • signs of an electrolyte imbalance--increased thirst or urination, confusion, vomiting, constipation, muscle pain, leg cramps, bone pain, lack of energy, irregular heartbeats, tingly feeling.

Common side effects may include:

  • weakness;
  • feeling like you might pass out;
  • severe pain in your upper stomach spreading to your back, nausea and vomiting;
  • fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath; or
  • electrolyte imbalance.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Microzide (Hydrochlorothiazide Capsule)

SLIDESHOW

How to Lower Blood Pressure: Exercise Tips See Slideshow
Microzide Professional Information

SIDE EFFECTS

The adverse reactions associated with hydrochlorothiazide have been shown to be dose related. In controlled clinical trials, the adverse events reported with doses of 12.5 mg hydrochlorothiazide once daily were comparable to placebo. The following adverse reactions have been reported for doses of hydrochlorothiazide 25 mg and greater and, within each category, are listed in the order of decreasing severity.

Body as a whole: Weakness.

Cardiovascular: Hypotension including orthostatic hypotension (may be aggravated by alcohol, barbiturates, narcotics or antihypertensive drugs).

Digestive: Pancreatitis, jaundice (intrahepatic cholestatic jaundice), diarrhea, vomiting, sialadenitis, cramping, constipation, gastric irritation, nausea, anorexia.

Hematologic: Aplastic anemia, agranulocytosis, leukopenia, hemolytic anemia, thrombocytopenia.

Hypersensitivity: Anaphylactic reactions, necrotizing angiitis (vasculitis and cutaneous vasculitis), respiratory distress including pneumonitis and pulmonary edema, photosensitivity, fever, urticaria, rash, purpura.

Metabolic: Electrolyte imbalance (see PRECAUTIONS), hyperglycemia, glycosuria, hyperuricemia.

Musculoskeletal: Muscle spasm.

Nervous System/Psychiatric: Vertigo, paresthesia, dizziness, headache, restlessness.

Renal: Renal failure, renal dysfunction, interstitial nephritis (see WARNINGS).

Skin: Erythema multiforme including Stevens-Johnson syndrome, exfoliative dermatitis including toxic epidermal necrolysis, alopecia.

Special Senses: Transient blurred vision, xanthopsia.

Urogenital: Impotence.

Whenever adverse reactions are moderate or severe, thiazide dosage should be reduced or therapy withdrawn.

Read the entire FDA prescribing information for Microzide (Hydrochlorothiazide Capsule)

© Microzide Patient Information is supplied by Cerner Multum, Inc. and Microzide Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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