Midazolam Hydrochloride Syrup

Last reviewed on RxList: 3/8/2019
Midazolam Hydrochloride Syrup Patient Information Including Side Effects

Brand Names: Versed

Generic Name: midazolam (oral)

What is midazolam (Versed)?

Midazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen) that is used to sedate a person who is having a minor surgery, dental work, or other medical procedure.

Midazolam may also be used for purposes not listed in this medication guide.

What are the possible side effects of midazolam (Versed)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication, alcohol, or other drugs that can slow your breathing. Your caregivers will watch you for symptoms such as weak or shallow breathing.

Tell your caregivers right away if you have:

The sedative effects of midazolam may last longer in older adults. You may need help getting out of bed for at least the first 8 hours. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury.

Common side effects may include:

  • amnesia or forgetfulness after your procedure;
  • drowsiness, dizziness;
  • nausea, vomiting; or
  • blurred vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about midazolam (Versed)?

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication. Midazolam is given in a hospital, dentist office, or other clinic setting where your vital signs can be watched closely.

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Midazolam Hydrochloride Syrup Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking midazolam (Versed)?

You should not use midazolam if you are allergic to it, or if you have:

Tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breastfeeding.

How should I take midazolam (Versed)?

Midazolam is usually given as a single dose just before your surgery or procedure.

Midazolam can slow or stop your breathing, especially if you have recently used an opioid medication. Midazolam should be used only in a hospital, dentist office, or other clinic setting where any serious side effects can be quickly treated.

After you take midazolam, you will be watched closely to make sure the medicine is working and does not cause harmful side effects.

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are in surgery.

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Midazolam Hydrochloride Syrup Patient Information including If I Miss a Dose

What happens if I miss a dose (Versed)?

Because you will receive midazolam in a clinical setting, you are not likely to miss a dose.

What happens if I overdose (Versed)?

Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.

What should I avoid after taking midazolam (Versed)?

Do not drink alcohol shortly after taking midazolam. This medicine can increase the effects of alcohol, which could be dangerous.

Grapefruit and grapefruit juice may interact with midazolam and lead to potentially dangerous effects. Avoid the use of grapefruit products for a short time after taking midazolam.

Midazolam can cause extreme drowsiness that may last for 24 to 48 hours after the injection. Older adults may feel sleepy for even longer.

Avoid driving or hazardous activity until the effects of midazolam have worn off completely. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

What other drugs will affect midazolam (Versed)?

Shortly after you are treated with midazolam, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Other drugs may affect midazolam, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Versed)?

Your doctor or pharmacist can provide more information about midazolam.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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