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Minocin

Last reviewed on RxList: 11/4/2020
Minocin Side Effects Center

What Is Minocin Oral Suspension?

Minocin (minocycline hydrochloride) is a tetracycline antibiotic used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, and others.

What Are Side Effects of Minocin Oral Suspension?

Common side effects of Minocin include:

Tell your doctor if you have serious side effects of Minocin including:

  • stomach cramps,
  • diarrhea that is watery or bloody,
  • flu symptoms,
  • sores in your mouth and throat,
  • weakness,
  • dark colored urine,
  • unusual bleeding,
  • purple or red pinpoint spots under your skin,
  • fever,
  • skin rash,
  • bruising,
  • severe tingling or numbness,
  • muscle weakness,
  • loss of appetite,
  • yellowing of the skin or eyes,
  • chest pain,
  • irregular heart rhythm,
  • cough,
  • wheezing,
  • shortness of breath,
  • confusion,
  • vomiting,
  • swelling,
  • weight gain,
  • urinating less than usual or not at all,
  • headache or pain behind your eyes,
  • ringing in your ears,
  • vision problems,
  • joint pain or swelling with fever,
  • swollen glands,
  • muscle aches,
  • general ill feeling,
  • unusual thoughts or behavior,
  • seizures (convulsions), or
  • a severe skin reaction.

Dosage for Minocin Oral Suspension

The usual dosage of Minocin is 200 mg initially followed by 100 mg every 12 hours.

What Drugs, Substances, or Supplements Interact with Minocin Oral Suspension?

Minocin may interact with other antibiotics, acetaminophen (Tylenol), isotretinoin, methotrexate, antifungals, blood thinners, cholesterol medications, heart or blood pressure medicines, migraine headache medicines, or NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications and supplements you use. Minocin should not be used during pregnancy. It could harm the fetus or cause permanent tooth discoloration later in life. Tell your doctor if you become pregnant during treatment. Minocin can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) while using minocycline.

Minocin Oral Suspension During Pregnancy and Breastfeeding

This drug passes into breast milk and may affect bone and tooth development in a nursing baby. Do not breastfeed while taking Minocin.

Additional Information

Our Minocin (minocycline hydrochloride) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Minocin Consumer Information

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, fever, swollen glands, joint pain, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Call your doctor at once if you have:

  • bronchospasm (wheezing, chest tightness, trouble breathing);
  • a seizure;
  • kidney problems--little or no urination, swelling in your feet or ankles, feeling tired or short of breath;
  • low blood cell counts--fever, chills, tiredness, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath;
  • increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, vision problems, pain behind your eyes; or
  • signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), nausea or vomiting, loss of appetite, easy bruising or bleeding, dark urine, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • numbness, tingling, burning pain;
  • hair loss;
  • discoloration of you skin or nails.
  • dizziness, spinning sensation;
  • muscle or joint pain;
  • nausea, diarrhea, loss of appetite;
  • swollen tongue, cough, trouble swallowing;
  • rash, itching; or
  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Minocin (Minocycline Hydrochloride Oral Suspension)

QUESTION

Bowel regularity means a bowel movement every day. See Answer
Minocin Professional Information

SIDE EFFECTS

Due to oral minocycline’s virtually complete absorption, side effects to the lower bowel, particularly diarrhea, have been infrequent. The following adverse reactions have been observed in patients receiving tetracyclines.

Body as a whole: Fever, and discoloration of secretions.

Gastrointestinal: Anorexia, nausea, vomiting, diarrhea, dyspepsia, stomatitis, glossitis, dysphagia, enamel hypoplasia, enterocolitis, pseudomembranous colitis, pancreatitis, inflammatory lesions (with monilial overgrowth) in the oral and anogenital regions.

Genitourinary: Vulvovaginitis.

Hepatic toxicity: Hyperbilirubinemia, hepatic cholestasis, increases in liver enzymes, fatal hepatic failure, and jaundice. Hepatitis, including autoimmune hepatitis, and liver failure have been reported (see PRECAUTIONS).

Skin: Alopecia, erythema nodosum, hyperpigmentation of nails, pruritus, toxic epidermal necrolysis, vasculitis, maculopapular rash and erythematous rash. Exfoliative dermatitis has been reported. Fixed drug eruptions, including balanitis, have been reported. Erythema multiforme and Stevens-Johnson syndrome have been reported. Photosensitivity is discussed above (see WARNINGS). Pigmentation of the skin and mucous membranes has been reported.

Respiratory: Cough, dyspnea, bronchospasm, exacerbation of asthma, and pneumonitis.

Renal toxicity: Interstitial nephritis. Elevations in BUN have been reported and are apparently dose related (see WARNINGS). Reversible acute renal failure has been reported.

Musculoskeletal: Arthralgia, arthritis, bone discoloration, myalgia, joint stiffness, and joint swelling.

Hypersensitivity reactions: Urticaria, angioneurotic edema, polyarthralgia, anaphylaxis/anaphylactoid reaction (including shock and fatalities), anaphylactoid purpura, myocarditis, pericarditis, exacerbation of systemic lupus erythematosus and pulmonary infiltrates with eosinophilia have been reported. A transient lupus-like syndrome and serum sickness-like reactions also have been reported.

Blood: Agranulocytosis, hemolytic anemia, thrombocytopenia, leukopenia, neutropenia, pancytopenia, and eosinophilia have been reported.

Central Nervous System: Convulsions, dizziness, hypesthesia, paresthesia, sedation, and vertigo. Pseudotumor cerebri (benign intracranial hypertension) in adults and bulging fontanels in infants (see PRECAUTIONS - General). Headache has also been reported.

Other: Thyroid cancer has been reported in the post-marketing setting in association with minocycline products. When minocycline therapy is given over prolonged periods, monitoring for signs of thyroid cancer should be considered. When given over prolonged periods, tetracyclines have been reported to produce brown-black microscopic discoloration of the thyroid gland. Cases of abnormal thyroid function have been reported.

Tooth discoloration in children less than 8 years of age (see WARNINGS) and also, in adults has been reported.

Oral cavity discoloration (including tongue, lip, and gum) has been reported.

Tinnitus and decreased hearing have been reported in patients on MINOCIN (minocycline hydrochloride).

The following syndromes have been reported. In some cases involving these syndromes, death has been reported. As with other serious adverse reactions, if any of these syndromes are recognized, the drug should be discontinued immediately:

Hypersensitivity syndrome consisting of cutaneous reaction (such as rash or exfoliative dermatitis), eosinophilia, and one or more of the following: hepatitis, pneumonitis, nephritis, myocarditis, and pericarditis. Fever and lymphadenopathy may be present.

Lupus-like syndrome consisting of positive antinuclear antibody; arthralgia, arthritis, joint stiffness, or joint swelling; and one or more of the following: fever, myalgia, hepatitis, rash, and vasculitis.

Serum sickness-like syndrome consisting of fever; urticaria or rash; and arthralgia, arthritis, joint stiffness, or joint swelling and lymphadenopathy. Eosinophilia may be present.

To report SUSPECTED ADVERSE REACTIONS, contact Valeant Pharmaceuticals North America LLC at 1-800-321-4576 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Read the entire FDA prescribing information for Minocin (Minocycline Hydrochloride Oral Suspension)

Related Resources for Minocin

© Minocin Patient Information is supplied by Cerner Multum, Inc. and Minocin Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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