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Minoxidil

Last reviewed on RxList: 10/29/2018
Minoxidil Side Effects Center

Last reviewed on RxList 10/29/2018

Minoxidil is a vasodilator used to treat high blood pressure (hypertension). Minoxidil is usually given together with two other medications including a diuretic (water pill). Minoxidil is available in generic form. Common side effects of Minoxidil include:

  • dizziness,
  • drowsiness,
  • tiredness, and
  • temporary edema (swelling) while taking this medication, especially during the first few weeks as your body adjusts to the lower blood pressure. This is normal.

If these side effects of Minoxidil persist or worsen, tell your doctor promptly. Other side effects of Minoxidil include:

  • nausea,
  • vomiting,
  • breast pain or tenderness, or
  • changes in the color, length, or thickness of body or facial hair.

The recommended initial dosage of Minoxidil tablets is 5 mg of given as a single daily dose. The effective dosage range is usually 10 to 40 mg per day. Minoxidil can interact with guanethidine. There may be other drugs that can interact with minoxidil. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor. During pregnancy, Minoxidil should be used only when prescribed. This drug passes into breast milk but is unlikely to have undesirable effects on a nursing infant. Consult your doctor before breastfeeding.

Our Minoxidil (minoxidil) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Minoxidil Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • new or worsening chest pain;
  • chest pain spreading to your jaw or shoulder;
  • fast or pounding heartbeats;
  • swelling in your legs, ankles, or feet;
  • rapid weight gain, especially in your face and midsection;
  • shortness of breath;
  • a light-headed feeling, like you might pass out;
  • fluid build-up in the lungs--pain when you breathe, feeling short of breath while lying down, wheezing, gasping for breath, cough with foamy mucus; or
  • severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common side effects may include:

  • changes in color, length, or thickness of body or facial hair;
  • nausea, vomiting;
  • rash; or
  • breast pain or tenderness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Minoxidil (Minoxidil Tablets)

QUESTION

Salt and sodium are the same. See Answer
Minoxidil Professional Information

SIDE EFFECTS

  1. Salt and Water Retention (see WARNINGS: Concomitant Use of an Adequate Diuretic is Required)-Temporary edema developed in 7% of patients who were not edematous at the start of therapy.
  2. Pericarditis, Pericardial Effusion, and Tamponade (see WARNINGS).
  3. Dermatologic-Hypertrichosis-Elongation, thickening, and enhanced pigmentation of fine body hair are seen in about 80% of patients taking minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) tablets. This develops within 3 to 6 weeks after starting therapy. It is usually first noticed on the temples, between the eyebrows, between the hairline and the eyebrows, or in the side-burn area of the upper lateral cheek, later extending to the back, arms, legs, and scalp. Upon discontinuation of minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) , new hair growth stops, but 1 to 6 months may be required for restoration to pretreatment appearance. No endocrine abnormalities have been found to explain the abnormal hair growth; thus, it is hypertrichosis without virilism. Hair growth is especially disturbing to children and women and such patients should be thoroughly informed about this effect before therapy with minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) is begun. Allergic-Rashes have been reported, including rare reports of bullous eruptions, and Stevens-Johnson Syndrome.
  4. Hematologic-Thrombocytopenia and leukopenia (WBC < 3000/mm3) have rarely been reported.
  5. Gastrointestinal-Nausea and/or vomiting has been reported. In clinical trials the incidence of nausea and vomiting associated with the underlying disease has shown a decrease from pretrial levels.
  6. Miscellaneous-Breast tenderness-This developed in less than 1% of patients.
  7. Altered Laboratory Findings-(a) ECG changes-Changes in direction and magnitude of the ECG T-waves occur in approximately 60% of patients treated with minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) . In rare instances a large negative amplitude of the T-wave may encroach upon the S-T segment, but the S-T segment is not independently altered. These changes usually disappear with continuance of treatment and revert to the pretreatment state if minoxidil (minoxidil (minoxidil (minoxidil tablets) tablets) tablets) is discontinued. No symptoms have been associated with these changes, nor have there been alterations in blood cell counts or in plasma enzymeconcentrations that would suggest myocardial damage. Long-term treatment of patients manifesting such changes has provided no evidence of deteriorating cardiac function. At present the changes appear to be nonspecific and without identifiable clinical significance. (b)-Effects of hemodilution-hematocrit, hemoglobin and erythrocyte count usually fall about 7% initially and then recover to pretreatment levels. (c) Other-Alkaline phosphatase increased varyingly without other evidence of liver or bone abnormality. Serum creatinine increased an average of 6% and BUN slightly more, but later declined to pretreatment levels.

Read the entire FDA prescribing information for Minoxidil (Minoxidil Tablets)

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© Minoxidil Patient Information is supplied by Cerner Multum, Inc. and Minoxidil Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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