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Mirapex vs. Inbrija

Reviewed on 7/30/2019

Are Mirapex and Inbrija the Same Thing?

Mirapex (pramipexole) and Inbrija (levodopa inhalation powder) are used to treat symptoms of Parkinson's disease.

Mirapex is also used to treat restless legs syndrome.

Mirapex and Inbrija belong to different rug classes. Mirapex is a dopamine agonist and Inbrija is an aromatic amino acid.

Side effects of Mirapex and Inbrija that are similar include nausea.

Side effects of Mirapex that are different from Inbrija include dizziness on standing (postural hypotension), vomiting, dry mouth, stomach pain, constipation, headache, dizziness, spinning sensation, drowsiness, swelling in your hands and feet, appetite or weight changes, blurred vision, sleep problems (insomnia or unusual dreams), memory problems (amnesia or forgetfulness), confusion or thinking problems, swelling in your hands or feet, impotence, loss of interest in sex, and trouble having an orgasm.

Side effects of Inbrija that are different from Mirapex include cough, upper respiratory tract infection, and discolored mucus.

Both Mirapex and Inbrija may interact with metoclopramide.

Mirapex may also interact with alcohol, other drugs that make you drowsy (narcotics, sleeping pills, muscle relaxers, or medicines for anxiety or seizures), cimetidine, and medicines to treat mental illness.

Inbrija may also interact with monoamine oxidase inhibitors (MAOIs), dopamine D2 receptor antagonists (e.g., phenothiazines, butyrophenones, risperidone), isoniazid, and iron salts or multivitamins containing iron salts.

Do not stop using Mirapex or Inbrija suddenly, or you could have unpleasant withdrawal symptoms.

What Are Possible Side Effects of Mirapex?

Common side effects of Mirapex include:

  • dizziness when standing (postural hypotension)
  • nausea
  • dry mouth
  • stomach pain
  • vomiting
  • constipation
  • headache
  • dizziness
  • spinning sensation
  • drowsiness
  • swelling in your hands and feet
  • appetite or weight changes
  • blurred vision
  • sleep problems (insomnia or unusual dreams)
  • memory problems (amnesia)
  • forgetfulness
    confusion or thinking problems
  • swelling in your hands or feet
  • impotence
  • loss of interest in sex, or
  • trouble having an orgasm

What Are Possible Side Effects of Inbrija?

Common side effects of Inbrija include:

  • cough,
  • nausea,
  • upper respiratory tract infection, and
  • discolored mucus

What Is Mirapex?

Mirapex (pramipexole) is a dopamine agonist medication used to treat symptoms of Parkinson's disease, and restless legs syndrome.

What Is Inbrija?

Inbrija (levodopa inhalation powder) is an aromatic amino acid indicated for the intermittent treatment of OFF episodes in patients with Parkinson's disease treated with carbidopa/levodopa.

QUESTION

Parkinson's disease is only seen in people of advanced age. See Answer

What Drugs Interact With Mirapex?

Mirapex may interact with cold or allergy medicines, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety, other medicines for Parkinson's disease, medicine to prevent or treat nausea and vomiting, or medicine to treat psychiatric disorders.

Mirapex may also interact with amantadine, cimetidine, diltiazem, ranitidine, quinidine, quinine, triamterene, verapamil, promethazine, and levodopa.

What Drugs Interact With Inbrija?

Inbrija may interact with monoamine oxidase inhibitors (MAOIs), dopamine D2 receptor antagonists (e.g., phenothiazines, butyrophenones, risperidone, metoclopramide), isoniazid, and iron salts or multivitamins containing iron salts. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Inbrija; it may harm a fetus. Inbrija passes into breast milk and may interfere with lactation. Consult your doctor before breastfeeding. Withdrawal symptoms may occur if you suddenly stop taking Inbrija.

How Should Mirapex Be Taken?

Mirapex is taken in tablet form three times per day.

How Should Inbrija Be Taken?

The dose of Inbrija is oral inhalation of the contents of two Inbrija capsules (84 mg) as needed for OFF symptoms, up to 5 times daily.

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References

Boehringer Ingelheim. Mirapex Product Information.
https://docs.boehringer-ingelheim.com/Prescribing%20Information/PIs/Mirapex/Mirapex.pdf
Acorda Therapeutics. Inbrija Product Information.
www.inbrija.com/?
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