Monistat Vaginal Cream Side Effects Center

Last updated on RxList: 7/27/2022
Monistat Vaginal Cream Side Effects Center

What Is Monistat Vaginal Cream?

Monistat Vaginal Cream (miconazole nitrate vaginal cream) is an azole antifungal medication used to treat vaginal candida (yeast) infections. Some formulations of this medication are available in generic form and over-the-counter (OTC).

What Are Side Effects of Monistat Vaginal Cream?

Common side effects of Monistat Vaginal Cream include:

  • burning,
  • stinging,
  • swelling,
  • irritation,
  • redness,
  • pimple-like bumps,
  • tenderness,
  • itching,
  • pain, or flaking of the treated skin;
  • headache,
  • burning/itching/pain in the vagina or urinary opening;
  • an increased need to urinate, or
  • lower abdominal cramps.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Monistat Vaginal Cream

Monistat Vaginal Cream is usually used once/daily at bedtime, and applied directly into the vagina. Read the instructions for application information.

What Drugs, Substances, or Supplements Interact with Monistat Vaginal Cream?

Monistat Vaginal Cream may adversely interact with warfarin, oral antibiotics, or drugs that suppress the immune system. Discuss all medications you are taking with your doctor.

Monistat Vaginal Cream During Pregnancy or Breastfeeding

This medication should be used only when advised by your doctor during pregnancy. Discuss the risks and benefits with your doctor. It is not known whether this drug passes into breast milk. Breast-feeding while using this drug is not recommended. Consult your doctor before breastfeeding.

Additional Information

Our Monistat Vaginal Cream Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Monistat Vaginal Cream Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

  • mild burning or itching;
  • skin irritation around the vagina; or
  • urinating more than usual.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Monistat Vaginal Cream Professional Information


The following side effects have been reported with the use of miconazole nitrate vaginal cream; a temporary increase in burning, itching, and/or irritation when the cream is inserted. Abdominal cramping, headaches, hives, and skin rash have also been reported. If any of these occur, stop using miconazole nitrate vaginal cream and consult your doctor.

Read the entire FDA prescribing information for Monistat Vaginal Cream (Miconazole Nitrate Vaginal Cream)

© Monistat Vaginal Cream Patient Information is supplied by Cerner Multum, Inc. and Monistat Vaginal Cream Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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