Monoclate-P Side Effects Center

Last updated on RxList: 5/6/2022
Monoclate-P Side Effects Center

What Is Monoclate-P?

Monoclate-P [Antihemophilic Factor (Human), Factor VIII: C Pasteurized, Monoclonal Antibody Purified] is a naturally occurring protein in the blood used to treat or prevent bleeding episodes in adults and children with hemophilia A. Monoclate-P is also used to control bleeding related to surgery or dentistry in a person with hemophilia. Monoclate-P is not for use in people with von Willebrand disease. Monoclate-P is available in generic form.

What Are Side Effects of Monoclate-P?

Common side effects of Monoclate-P include:

  • mild nausea or stomach pain
  • tingly or jittery feeling
  • blurred vision
  • headache
  • chills
  • allergic reactions, or
  • injection site reactions (swelling, stinging, or irritation)

Dosage for Monoclate-P

Dosage of Monoclate-P must be individualized according to the needs of the patient (weight, severity of hemorrhage, presence of inhibitors).

What Drugs, Substances, or Supplements Interact with Monoclate-P?

Monoclate-P may interact with other drugs. Tell your doctor all medications and supplements you use.

Monoclate-P During Pregnancy or Breastfeeding

Monoclate-P may be harmful to a fetus. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Additional Information

Our Monoclate-P [Antihemophilic Factor (Human), Factor VIII:C Pasteurized, Monoclonal Antibody Purified] Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Monoclate-P Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; chest tightness, wheezing, difficult breathing; feeling light-headed, fainting; swelling of your face, lips, tongue, or throat.

Stop using human antihemophilic factor and call your doctor at once if you have:

  • tingly feeling in your face, ears, or arms;
  • headache, blurred vision, feeling jittery;
  • fever, chills, drowsiness, and runny nose followed by skin rash and joint pain 2 weeks later; or
  • nausea, vomiting, upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • swelling, stinging, or irritation where the injection was given;
  • chills;
  • mild nausea; or
  • allergic reaction.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Monoclate-P Professional Information


Products of this type are known to cause allergic reactions, mild chills, nausea or stinging at the infusion site. In some cases, inhibitors of FVIII may occur.

Read the entire FDA prescribing information for Monoclate-P (Antihemophilic Factor)

© Monoclate-P Patient Information is supplied by Cerner Multum, Inc. and Monoclate-P Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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