What are the Most Common Causes of Atrial Fibrillation?

Reviewed on 6/16/2020

How does atrial fibrillation occur?

Atrial fibrillation (AF)
Most common causes leading to atrial fibrillation include heart valve disease, heart failure, and others.

Atrial fibrillation (AF) is an abnormal heart rhythm characterized by an irregular and fast heartbeat. The upper chambers of the heart (atria) beat chaotically.  This can cause pooling and clotting of blood in the atria, instead of it emptying into the lower chamber (ventricles). AF can lead to stroke, heart failure, blood clots, and heart-related complications.

In the United States, approximately 5 million people are affected by atrial fibrillation. Atrial fibrillation classified into three types:

  • Paroxysmal atrial fibrillation: AF attacks that last for less than 24 hours
  • Persistent atrial fibrillation: AF attacks that last for more than seven days and require treatment
  • Long-standing persistent atrial fibrillation: AF that has continued for more than a year

Most common causes leading to atrial fibrillation include:

What are the signs of AF?

Frequently, persons with AF have no symptoms. Symptoms and signs of AF include:

How is atrial fibrillation diagnosed?

The tests commonly used in evaluating a patient with atrial fibrillation are:

How is atrial fibrillation treated?

The goals of the treatment  of AF are

  • Regaining a normal heart rhythm,
  • Controlling heart rate,
  • Preventing blood clots, and
  • Mitigating the risk of stroke.

The various treatment options include drug therapy, surgery and lifestyle changes. Medications commonly used to treat atrial fibrillation are:

  • Antiarrhythmic drugs: Medications such as procainamide and amiodarone help to treat irregular heartbeats.
  • Rate control medications: Medications such as digoxin, metoprolol and verapamil control the heart rate.
  • Anticoagulant medications: Medications such as warfarin prevent the formation of clots.

When drug therapy fails, procedures to treat atrial fibrillation include:

  • Electrical cardioversion: Restoring normal heart rhythm by using electrical shock with the patient under anesthesia.
  • Pulmonary vein ablation: Applying radiofrequency energy or freezing to excitable electrical tissue around the connections of the pulmonary vein near the atrium.
  • Ablation of the AV node: A catheter is directed to the heart through the groin. A small area of tissue around the junction connecting the upper (atria) and lower (ventricles) chambers of heart is destroyed with radiofrequency energy.
  • Patients with a slow heart rate may have a pacemaker installed with a pulse generator and wires that transmit electric impulses to the heart.
  • Left atrial appendage closure: A small, ear-shaped sac present in the muscle wall of the atrium that is closed to prevent stroke.

Some patients, who have had failed drug therapy and catheter ablation or with blood clots in the left atrium, recent stroke and an enlarged left atrium may be suitable for surgical treatment:

  • Maze procedure: This procedure involves a series of cuts made in the upper chambers of the heart to block any abnormal electrical impulse.
  • Excision of the left atrial appendage: Surgical removal of left atrial appendage.

Lifestyle changes for AF include:

Can a person die from atrial fibrillation?

Atrial fibrillation is a serious condition that, if untreated, doubles the risks of heart-related deaths and stroke. It is associated with 1.5 to 1.9-fold higher risk of death. So, it is important to control atrial fibrillation.


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