Motrin (ibuprofen) vs. Naproxen (anaprox)

Are Ibuprofen and Naproxen the Same Thing?

Motrin (ibuprofen) and Naprosyn (naproxen) are nonsteroidal anti-inflammatory drugs (NSAIDs) indicated for relief of mild to moderate pain, fever, and inflammation, and for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis.

Motrin and Naprosyn are available over-the-counter (OTC) and in generic form.

A difference is that in general, a dose Motrin is taken every 4 to 6 hours, while a dose of Naprosyn is taken every 8 to 12 hours.

What Are Possible Side Effects of Ibuprofen?

Common side effects of Ibuprofen include:

Other side effects of Motrin may occur. Consult your physician if you experience any possible side effects of Motrin.

What Are Possible Side Effects of Naproxen?

Common side effects of Naproxen include:

  • heartburn,
  • stomach or abdominal pain,
  • upset stomach,
  • nausea,
  • diarrhea,
  • constipation,
  • bloating,
  • gas,
  • dizziness,
  • nervousness,
  • skin rash,
  • headache,
  • blurred vision,
  • ringing in your ears, and
  • itching.

What is Ibuprofen?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) indicated for relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis, for relief of mild to moderate pain, and for treatment of primary dysmenorrhea. A generic formulation is available.

What is Naproxen?

Naproxen is considered a nonsteroidal anti-inflammatory drug (NSAID) and is used for pain management for many diseases, arthritic diseases, and inflammatory diseases such as tendonitis, bursitis, and gout.

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What Drugs Interact With Ibuprofen?

Ibuprofen may interact with other drugs. Tell your doctor all medications and supplements you use.

What Drugs Interact With Naproxen?

Naproxen may interact with antidepressants, blood thinners, lithium, methotrexate, diuretics (water pills), steroids, aspirin or other NSAIDs, or heart or blood pressure medications. Tell your doctor all medications and supplements you use. Naprosyn may cause premature closing of the ductus arteriosus in the fetus and does enter breast milk; avoidance of the drug in pregnant and breastfeeding women is suggested.

How Should Ibuprofen Be Taken?

The recommended dose of Motrin should be adjusted to suit individual patients needs but should not exceed 3200 mg in the total daily dose. Use of alcohol and smoking could increase side effects. Safe use of Motrin for use by children has not been established. It is not known whether ibuprofen is harmful to an unborn baby.

How Should Naproxen Be Taken?

Naproxen is available in several doses and drug configurations; Naproxen tablets with strengths of 250, 375 and 500 mg and as an oral suspension containing 125 mg Naproxen per 5 ml of liquid, EC-Naproxen (delayed release to reduce gastric irritation) with strengths of 375 and 500 mg, Anaprox in 275 mg tablets, Anaprox DS in 550 mg tablets. Almost all Naproxen drugs are recommended to be dosed twice per day (every 12 hours) with children's doses (strength in mg per Kg) based on the child's weight, also twice a day with a maximum dose of 15 mg per Kg per day.

Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

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If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References

RxList. Motrin Product Monograph.
https://www.rxlist.com/ibuprofen-drug.htm
RxList. Naprosyn (naproxen) Prescribing Information.
https://www.rxlist.com/naprosyn-side-effects-drug-center.htm

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