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Last reviewed on RxList: 12/29/2008
Mumpsvax Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 8/18/2015

Mumpsvax (mumps virus vaccine live) is an immunization used to help prevent mumps in children. Mumpsvax is available in generic form. Common side effects of Mumpsvax include: 

  • burning or stinging where the shot was given,
  • low fever,
  • fussiness or crying,
  • cough,
  • runny nose, or
  • diarrhea.

Tell your doctor if your child experiences a serious side effect of Mumpsvax including

  • problems with hearing or vision,
  • extreme drowsiness,
  • fainting,
  • fussiness/irritability/crying for an hour or longer,
  • easy bruising or bleeding,
  • weakness,
  • seizures (black-out or convulsions),
  • high fever (within a few hours or a few days after the vaccine), or
  • swelling of the testicles (scrotum) in a male child.

The dose of Mumpsvax for any age is 0.5 mL administered subcutaneously, preferably into the outer aspect of the upper arm. The recommended age for primary vaccination is 12 to 15 months. Mumpsvax may interact with steroids, medicines to treat or prevent organ transplant rejection, or medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders. Tell your doctor all medications and supplements you use and all vaccines you recently received. A woman should avoid becoming pregnant for at least 3 months after receiving a mumps vaccine. Consult your doctor before breastfeeding.

Our Mumpsvax (mumps virus vaccine live) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Mumpsvax Consumer Information

Keep track of any and all side effects your child has after receiving this vaccine. If the child ever receives a booster dose, you will need to tell the doctor if the previous shots caused any side effects.

Becoming infected with mumps is much more dangerous to your child's health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if the child has any of these serious side effects:

  • problems with hearing or vision;
  • extreme drowsiness, fainting;
  • fussiness, irritability, crying for an hour or longer;
  • easy bruising or bleeding, weakness;
  • seizure (black-out or convulsions);
  • high fever (within a few hours or a few days after the vaccine); or
  • swelling of the testicles (scrotum) in a male child.

Less serious side effects include:

  • burning or stinging where the shot was given;
  • low fever;
  • mild fussiness or crying;
  • cough, runny nose; or
  • diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

Read the entire detailed patient monograph for Mumpsvax (Mumps Virus Vaccine Live)

Mumpsvax Professional Information


The following adverse reactions are listed in decreasing order of severity, without regard to causality, within each body system category and have been reported during clinical trials, with use of the marketed vaccine, or with use of polyvalent vaccine containing mumps:

Body as a Whole

Fever; syncope; irritability.

Cardiovascular System


Digestive System

Pancreatitis; diarrhea; parotitis.

Endocrine System

Diabetes mellitus.

Hemic and Lymphatic System

Thrombocytopenia; purpura; lymphadenopathy; leukocytosis.

Immune System

Anaphylaxis and anaphylactoid reactions have been reported as well as related phenomena such as angioneurotic edema (including peripheral or facial edema) and bronchial spasm in individuals with or without an allergic history.

Nervous System

Encephalitis; Guillain-Barré Syndrome (GBS); febrile seizures; ocular palsies.

Cases of aseptic meningitis have been reported to VAERS following measles, mumps, and rubella vaccination. Although a causal relationship between the Urabe strain of mumps vaccine and aseptic meningitis has been shown, there are no data to link Jeryl Lynn mumps vaccine to aseptic meningitis.

Respiratory System

Cough; rhinitis.


Stevens-Johnson Syndrome; erythema multiforme; urticaria.

Local reactions including burning/stinging at injection site; wheal and flare.

Special Senses - Ear

Nerve deafness; otitis media.

Special Senses - Eye

Optic neuritis; papillitis; retrobulbar neuritis; conjunctivitis.

Urogenital System



Death from various, and in some cases unknown, causes has been reported rarely following vaccination with measles, mumps, and rubella vaccines; however, a causal relationship has not been established. No deaths or permanent sequelae were reported in a published post-marketing surveillance study in Finland involving 1.5 million children and adults who were vaccinated with M-M-R II during 1982-1993.33

Under the National Childhood Vaccine Injury Act of 1986, health-care providers and manufacturers are required to record and report certain suspected adverse events occurring within specific time periods after vaccination. However, the U.S. Department of Health and Human Services (DHHS) has established a Vaccine Adverse Event Reporting System (VAERS) which will accept all reports of suspected events.32 A VAERS report form as well as information regarding reporting requirements can be obtained by calling VAERS 1-800-822-7967.

Read the entire FDA prescribing information for Mumpsvax (Mumps Virus Vaccine Live)

Related Resources for Mumpsvax

© Mumpsvax Patient Information is supplied by Cerner Multum, Inc. and Mumpsvax Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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